898265-48-0

Basic information

• Product Name: Methyl trans-4-AMino-1-AdaMantane Carboxylate
• Synonyms: Methyl trans-4-AMino-1-AdaMantane Carboxylate;(E)-4-Aminoadamantane-1-carboxylic acid methyl ester;Tricyclo[3.3.1.13,7]decane-1-carboxylicacid,4-amino-,methylester,hydrochloride(1:1),stereoisomer
• CAS NO: 898265-48-0
• Molecular Formula: C12H19NO2
• Molecular Weight: 209.28476
• Mol File: 898265-48-0.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl trans-4-AMino-1-AdaMantane Carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl trans-4-AMino-1-AdaMantane Carboxylate(898265-48-0)
• EPA Substance Registry System: Methyl trans-4-AMino-1-AdaMantane Carboxylate(898265-48-0)

Safety Data

• Hazardous Substances Data: 898265-48-0(Hazardous Substances Data)

Usage

Description

Methyl trans-4-amino-1-adamantane carboxylate is a chemical compound characterized by its molecular formula C12H19NO2. It is an adamantane derivative, known for its rigid and bulky adamantane moiety, along with an amino group and a carboxylate group. These structural features make it a versatile intermediate in the synthesis of pharmaceuticals and organic compounds, with unique properties that are valuable for research and development in the pharmaceutical and chemical industries.

Uses

Used in Pharmaceutical Industry:
Methyl trans-4-amino-1-adamantane carboxylate is used as an intermediate in the synthesis of various biologically active molecules. Its distinct molecular structure, featuring an amino and carboxylate group, allows for the creation of compounds with potential therapeutic applications.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, Methyl trans-4-amino-1-adamantane carboxylate serves as a key building block for the development of new organic compounds. Its adamantane moiety provides a stable and rigid framework that can be further functionalized to yield a variety of chemical products with diverse applications.
Used in Research and Development:
Due to its unique structural properties and potential applications, Methyl trans-4-amino-1-adamantane carboxylate is utilized in research and development efforts within the pharmaceutical and chemical industries. It offers a promising platform for the exploration of new drug candidates and the advancement of synthetic methodologies.

Upstream product

• 1057343-95-9 (E)-4-amino-adamantane-1-carboxylic acid 
• 67-56-1 methanol 
• 56674-88-5 methyl 4-oxoadamantane-1-carboxylate 
• 20098-14-0 chemantane 
• 1057343-95-9 (E)-4-amino-adamantane-1-carboxylic acid 
• 1057343-95-9 (Z)-4-amino-adamantane-1-carboxyacid 
• 56674-87-4 4-oxoadamantane-1-carboxylic acid 
• 1057343-95-9 trans-4-aminoadamantane-1-carboxylic acid 
• 1057343-95-9 4-amino-adamantane-1-carboxylic acid 

Relevant articles and documents

NOVEL COMPOUND HAVING ABILITY TO INHIBIT 11B-HSD1 ENZYME OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT

The present invention relates to a novel compound or a pharmaceutically acceptable salt thereof inhibiting 11β-HSD1 enzyme activity, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient. Since the compound of the present invention selectively inhibits the activity of 11β-HSD1 (11β-Hydroxysteroid dehydrogenase type 1), the compound of the invention can be effectively used as a therapeutic agent for the treatment of diseases caused by the over-activation of 11β-HSD1 such as non-insulin dependent type II diabetes, insulin resistance, obesity, lipid disorder, metabolic syndrome, and other diseases or condition mediated by the excessive activity of glucocorticoid.

A COMPOUND FOR INHIBITING HUMAN 11-β-HYDROXY STEROID DEHYDROGENASE TYPE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention relates to a novel compound, or a stereoisomer, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for human-11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) comprising the same. The invention provides a compound, which has excellent activity and solubility and is more efficiently formulated and delivered, and a pharmaceutical composition for human-11-beta-hydroxysteroid dehydrogenase type 1 comprising the same.

TETRAHYDROQUINOXALINE UREA DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

The present invention relates to tetrahydroquinoxaline urea derivatives, to their preparation and to their therapeutic application.