886365-02-2

Basic information

• Product Name: 5-BROMO-4-METHYL-PYRIDINE-2-CARBOXYLIC ACID
• Synonyms: 5-BROMO-4-METHYL-PYRIDINE-2-CARBOXYLIC ACID;5-Bromo-4-methylpicolinic acid, 5-Bromo-2-carboxy-4-methylpyridine;5-BroMo-2-carboxy-4-Methylpyridine;5-broMo-4-Methylpicolinic acid;5-bromo-4-methyl-2-Pyridinecarboxylic acid
• CAS NO: 886365-02-2
• Molecular Formula: C₇H₆BrNO₂
• Molecular Weight: 216.03204
• Product Categories: Heterocycle-Pyridine series
• Mol File: 886365-02-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 335.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.692±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.48±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-4-METHYL-PYRIDINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-4-METHYL-PYRIDINE-2-CARBOXYLIC ACID(886365-02-2)
• EPA Substance Registry System: 5-BROMO-4-METHYL-PYRIDINE-2-CARBOXYLIC ACID(886365-02-2)

Safety Data

• Hazardous Substances Data: 886365-02-2(Hazardous Substances Data)

Usage

Description

5-Bromo-4-methyl-pyridine-2-carboxylic acid is a chemical compound characterized by the molecular formula C8H7BrNO2. It is a pyridine derivative featuring a bromine atom and a methyl group at the 5 and 4 positions, respectively, with a carboxylic acid functional group attached at the 2 position of the pyridine ring. 5-Bromo-4-methyl-pyridine-2-carboxylic acid is recognized for its potential applications across various fields, including pharmaceuticals, agrochemicals, and materials science, due to its diverse reactivity and capacity to engage in a wide array of chemical reactions. The carboxylic acid group endows this molecule with the potential to serve as a key building block in the synthesis of more complex organic molecules, and its distinctive chemical structure positions it as a significant intermediate in the development of specific drugs and pharmaceutical products.

Uses

Used in Pharmaceutical Industry:
5-Bromo-4-methyl-pyridine-2-carboxylic acid is utilized as a key intermediate in the synthesis of various pharmaceutical products. Its unique structure and functional groups contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Bromo-4-methyl-pyridine-2-carboxylic acid serves as a valuable building block for the creation of novel agrochemicals. Its reactivity and structural features are harnessed to produce compounds with applications in crop protection and pest management.
Used in Materials Science:
5-Bromo-4-methyl-pyridine-2-carboxylic acid is employed as a component in the development of advanced materials. Its chemical properties allow for its integration into materials with specific properties, such as those used in coatings, adhesives, or other industrial applications where unique chemical or physical characteristics are required.
Used in Organic Synthesis:
As a versatile organic molecule, 5-Bromo-4-methyl-pyridine-2-carboxylic acid is used as a starting material in organic synthesis. Its reactivity and the presence of the carboxylic acid group make it suitable for the preparation of a variety of complex organic compounds for research and industrial purposes.

Upstream product

• 1122090-38-3 potassium 5-bromo-4-methylpyridine-2-carboxylic acid 
• 886365-06-6 5-bromo-4-methyl-pyridine-2-carboxylic acid methyl ester 
• 3430-26-0 2,5-Dibromo-4-methylpyridine 
• 124-38-9 carbon dioxide 
• 1122090-37-2 5-bromo-4-methyl-2-vinyl-pyridine 

Downstream Products

• 886365-06-6 5-bromo-4-methyl-pyridine-2-carboxylic acid methyl ester 

Relevant articles and documents

BTK INHIBITORS

The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I, or pharmaceutically acceptable salts thereof, Formula I or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula I in the treatment of Btk mediated disorders.

7-AZAINDOLE INHIBITORS OF CRAC

Disclosed are compounds of Formula (I), useful for treatment of autoimmune and inflammatory diseases associated with IL-2 inhibition via modulation of calcium release-activated calcium (CRAC) channels. Also disclosed are methods of making and using the compounds for treatment of diseases associated with CRAC channels.

TRIAZOLOPYRIDINES

The present invention relates to triazolopyridine compounds of general formula (I) : in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said com