886364-50-7

Basic information

• Product Name: 1-(5-Bromo-2-pyridinyl)-2,2,2-trifluoroethanone
• Synonyms: 1-(5-Bromo-2-pyridinyl)-2,2,2-trifluoroethanone
• CAS NO: 886364-50-7
• Molecular Formula: C7H3BrF3NO
• Molecular Weight: 254
• Mol File: 886364-50-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 236℃
• Flash Point: 97℃
• Appearance: /
• Density: 1.730
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -1.40±0.10(Predicted)
• CAS DataBase Reference: 1-(5-Bromo-2-pyridinyl)-2,2,2-trifluoroethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-Bromo-2-pyridinyl)-2,2,2-trifluoroethanone(886364-50-7)
• EPA Substance Registry System: 1-(5-Bromo-2-pyridinyl)-2,2,2-trifluoroethanone(886364-50-7)

Safety Data

• Hazardous Substances Data: 886364-50-7(Hazardous Substances Data)

Usage

General Description

1-(5-Bromo-2-pyridinyl)-2,2,2-trifluoroethanone is a highly reactive chemical compound with the molecular formula C7H4BrF3NO. It is commonly used in organic synthesis and pharmaceutical research due to its unique chemical properties. 1-(5-Bromo-2-pyridinyl)-2,2,2-trifluoroethanone is a potent electrophile and can undergo various reactions such as nucleophilic addition and substitution. It is also known to have antimicrobial and antifungal properties and is used in the development of new drugs and pharmaceutical products. However, due to its reactivity and potential health hazards, it should be handled with caution and in accordance with proper safety protocols.

Upstream product

• 624-28-2 2,5-dibromopyridine 
• 383-63-1 ethyl trifluoroacetate, 
• 917397-92-3 1-(5-bromo-pyridin-2-yl)-2,2,2-trifluoroethanol 
• 31181-90-5 5-bromo-pyridine-2-carbaldehyde 
• 407-38-5 2,2,2-trifluoroethyl trifluoroacetate 

Downstream Products

• 1454907-29-9 benzyl[1-(5-bromopyridin-2-yl)-2,2,2-trifluoroethyl]amine 
• 1454907-30-2 1-((4R,5R)-5-{4-[6-(1-benzylamino-2,2,2-trifluoroethyl)pyridin-3-yl]phenyl}-4-fluoromethyl-2,2-dimethyloxazolidin-3-yl)-2,2-difluoroethanone 
• 1454907-31-3 1-((4R,5R)-5-{4-[6-(1-amino-2,2,2-trifluoroethyl)pyridin-3-yl]phenyl}-4-fluoromethyl-2,2-dimethyloxazolidin-3-yl)-2,2-difluoroethanone 
• 1454904-56-3 N-((1S,2R)-2-{4-[6-(1-amino-2,2,2-trifluoroethyl)pyridin-3-yl]phenyl}-1-fluoromethyl-2-hydroxyethyl)-2,2-difluoroacetamide 
• 1454907-33-5 2,2-difluoro-1-((4S,5R)-4-fluoromethyl-2,2-dimethyl-5-{4-[6-(2,2,2-trifluoro-1-methylaminoethyl)pyridin-3-yl]phenyl}oxazolidin-3-yl)ethanone 
• 1454907-28-8 benzyl-[1-(5-brompyridin-2-yl)-2,2,2-trifluoroeth-(E)-ylidene]amine 
• 1454904-57-4 2,2-difluoro-N-((1S,2R)-1-fluoromethyl-2-hydroxy-2-{4-[6-(2,2,2-trifluoro-1-methylaminoethyl)pyridin-3-yl]phenyl}ethyl)acetamide 
• 917397-92-3 1-(5-bromo-pyridin-2-yl)-2,2,2-trifluoroethanol 

Relevant articles and documents

PHENICOL ANTIBACTERIALS

The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.

REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE A AND B

The instant invention relates to compounds of formula I, diagrammed below, wherein R3, E, D and Y are defined in the application, which are useful as reversible inhibitors of monoamine oxidase-B and/or monoamine oxidase-A, and therefore useful to treat or prevent neurological diseases or conditions in mammals, preferably humans.