88609-02-3Relevant articles and documents
Novel scaffold hopping of potent benzothiazole and isatin analogues linked to 1,2,3-triazole fragment that mimic quinazoline epidermal growth factor receptor inhibitors: Synthesis, antitumor and mechanistic analyses
Rezki, Nadjet,Almehmadi, Meshal A.,Ihmaid, Saleh,Shehata, Ahmed M.,Omar, Abdelsattar M.,Ahmed, Hany E.A.,Aouad, Mohamed Reda
, (2020)
A series of benzothiazole/isatin linked to 1,2,3-triazole moiety and terminal sulpha drugs 5a-e and 6a-e were synthesized and evaluated for cytotoxic activity against a panel of cancer cell lines. The novel compounds showed variable IC50 range