885271-63-6

Basic information

• Product Name: METHYL-3-BROMOINDAZOLE-4-CARBOXYLATE
• Synonyms: Methyl 3-bromo-1H-indazole-4-carboxylate;Methyl 3-broMo-1H-indazol...;3-BroMo-1H-indazole-5-caboxylic acid Methylester;3-Bromo-4-(methoxycarbonyl)-1H-indazole;1H-INDAZOLE-4-CARBOXYLIC ACID,3-BROMO-,METHYL ESTER;methyl 3-bromo-2H-indazole-4-carboxylate
• CAS NO: 885271-63-6
• Molecular Formula: C₉H₇BrN₂O₂
• Molecular Weight: 255.08
• Mol File: 885271-63-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 399.7°C at 760 mmHg
• Flash Point: 195.5°C
• Appearance: /
• Density: 1.709g/cm³
• Vapor Pressure: 1.35E-06mmHg at 25°C
• Refractive Index: 1.675
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 10.25±0.40(Predicted)
• CAS DataBase Reference: METHYL-3-BROMOINDAZOLE-4-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL-3-BROMOINDAZOLE-4-CARBOXYLATE(885271-63-6)
• EPA Substance Registry System: METHYL-3-BROMOINDAZOLE-4-CARBOXYLATE(885271-63-6)

Safety Data

• Hazardous Substances Data: 885271-63-6(Hazardous Substances Data)

Usage

Description

METHYL-3-BROMOINDAZOLE-4-CARBOXYLATE, with the molecular formula C9H7BrN2O2, is a chemical compound derived from indazole, a five-membered aromatic heterocyclic compound. It is characterized by the presence of a bromine atom, which makes it a valuable precursor in organic synthesis and medicinal chemistry. This versatile intermediate is widely used in the synthesis of pharmaceutical and agrochemical compounds, including nonsteroidal anti-inflammatory drugs and antibacterial agents.

Uses

Used in Pharmaceutical Industry:
METHYL-3-BROMOINDAZOLE-4-CARBOXYLATE is used as a synthetic intermediate for the production of various pharmaceutical compounds. Its unique structure and bromine atom make it a promising candidate for drug discovery and development.
Used in Agrochemical Industry:
METHYL-3-BROMOINDAZOLE-4-CARBOXYLATE is also used as a building block in the synthesis of agrochemical compounds, contributing to the development of effective and innovative solutions for agricultural applications.
Used in Organic Synthesis:
As a valuable precursor in organic synthesis, METHYL-3-BROMOINDAZOLE-4-CARBOXYLATE is employed in the preparation of various organic compounds, facilitating the advancement of chemical research and the creation of novel molecules with potential applications in various fields.

InChI:InChI=1/C9H7BrN2O2/c1-14-9(13)5-3-2-4-6-7(5)8(10)12-11-6/h2-4H,1H3,(H,11,12)

Upstream product

• 18583-89-6 methyl 3-amino-2-methylbenzoate 
• 677306-38-6 1H-indazole-4-carboxylic acid 
• 192945-49-6 1H-indazole-4-carboxylic acid methyl ester 

Relevant articles and documents

Azacycle diketone compound and preparation method thereof (by machine translation)

The invention provides a azacyclodiketone compound which is characterized by being a compound represented by the following structure. The compound has inhibitory activity on cap-dependent endonuclease. (by machine translation)

INDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS

Disclosed indazoles compounds that are useful as antagonists of CCR1 activity and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.