884494-87-5

Basic information

• Product Name: 3-BROMO-5-CHLORO-2-FLUOROPYRIDINE
• Synonyms: 3-Bromo-5-chloro-2-fluoropyridine 3-Bromo-5-chloro-2-fluoropyridine;Pyridine,3-bromo-5-chloro-2-fluoro-
• CAS NO: 884494-87-5
• Molecular Formula: C₅H₂BrClFN
• Molecular Weight: 210.5
• Product Categories: Pyridine;Pyridine Series
• Mol File: 884494-87-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 204 °C at 760 mmHg
• Flash Point: 77.2 °C
• Appearance: /
• Density: 1.829 g/cm³
• Vapor Pressure: 0.000281mmHg at 25°C
• Refractive Index: 1.513
• Storage Temp.: Room temperature.
• PKA: -5.07±0.20(Predicted)
• CAS DataBase Reference: 3-BROMO-5-CHLORO-2-FLUOROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-5-CHLORO-2-FLUOROPYRIDINE(884494-87-5)
• EPA Substance Registry System: 3-BROMO-5-CHLORO-2-FLUOROPYRIDINE(884494-87-5)

Safety Data

• Hazard Codes: T
• Hazardous Substances Data: 884494-87-5(Hazardous Substances Data)

Usage

Description

3-Bromo-5-chloro-2-fluoropyridine is a pyridine derivative, a class of chemical compounds known for their diverse applications in various industries. This particular compound is highly reactive and versatile, serving as a crucial building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Its unique chemical structure and reactivity, along with its biological activities such as anti-inflammatory and anti-bacterial properties, make it a valuable asset in organic synthesis and medicinal chemistry. However, due to its potential hazards, it requires careful handling and storage.

Uses

Used in Pharmaceutical Industry:
3-Bromo-5-chloro-2-fluoropyridine is used as a key intermediate in the synthesis of various pharmaceuticals for its biological activities, including anti-inflammatory and anti-bacterial properties. It plays a significant role in the development of new drugs with improved therapeutic effects.
Used in Agrochemical Industry:
3-Bromo-5-chloro-2-fluoropyridine is used as a key intermediate in the production of a wide range of agrochemicals, including herbicides, insecticides, and fungicides. Its unique chemical structure and reactivity contribute to the effectiveness of these products in controlling pests and diseases in agriculture.
Used in Organic Synthesis:
3-Bromo-5-chloro-2-fluoropyridine is used as a valuable tool in organic synthesis due to its high reactivity and versatility. It serves as a building block for the synthesis of various complex organic compounds, enabling the development of new materials and chemical processes.
Used in Medicinal Chemistry:
3-Bromo-5-chloro-2-fluoropyridine is used in medicinal chemistry for its potential to contribute to the discovery and development of new drugs. Its unique properties and reactivity make it a promising candidate for the design and synthesis of novel therapeutic agents with improved efficacy and safety profiles.

InChI:InChI=1/C14H13F3N2/c1-18-8-10-2-4-11(5-3-10)13-7-6-12(9-19-13)14(15,16)17/h2-7,9,18H,8H2,1H3

Downstream Products

• 1242329-09-4 methyl 3-({6-[(5-chloro-3-bromopyridin-2-yl)oxy]-1-methyl-1H-benzimidazol-2-yl}methoxy)benzoate 
• 1372606-96-6 5-(4-chloro-phenyl)-6-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-pyridin-3-ylamine 
• 1372605-69-0 (S)-N-(5-(4-chlorophenyl)-6-(1,1,1-trifluoropropan-2-yloxy)pyridin-3-yl)pyridazine-3-carboxamide 
• 1372606-94-4 [5-(4-Chloro-phenyl)-6-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-pyridin-3-yl]-carbamic acid tert-butyl ester 
• 1364677-77-9 (S)-methyl 5-(4-chlorophenyl)-6-(1,1,1-trifluoropropan-2-yloxy)nicotinate 
• 1364677-79-1 (S)-5-(4-chlorophenyl)-6-(1,1,1-trifluoropropan-2-yloxy)nicotinic acid 
• 1364677-75-7 5-(4-chloro-3-(4-chloro-phenyl)-2-(S)-2,2,2-trifluoro-1-methyl-ethoxy)-pyridine 
• 1364677-73-5 5-chloro-3-(4-chloro-phenyl)-2-fluoro-pyridine