883442-46-4 Usage
Description
(4-Fluorotetrahydro-2H-pyran-4-yl)methanamine is a chemical compound characterized by its unique structure, which features a fluorinated tetrahydro-2H-pyran ring and an amine functional group. (4-fluorotetrahydro-2H-pyran-4-yl)methanamine is known for its potential applications in the pharmaceutical and chemical industries due to its versatile chemical properties.
Uses
Used in Pharmaceutical Industry:
(4-Fluorotetrahydro-2H-pyran-4-yl)methanamine is used as a reactant for the preparation of GPR40 agonists. GPR40 agonists are a class of drugs that target the G-protein coupled receptor 40, which plays a crucial role in insulin secretion and glucose homeostasis. These agonists are being investigated for their potential in treating type 2 diabetes and improving insulin sensitivity.
Additionally, (4-Fluorotetrahydro-2H-pyran-4-yl)methanamine is also used as a reactant for the synthesis of beta-secretase inhibitors. Beta-secretase, also known as BACE1, is an enzyme involved in the production of amyloid-beta peptides, which are implicated in the pathogenesis of Alzheimer's disease. Inhibiting this enzyme is a promising therapeutic strategy for the treatment of Alzheimer's disease, as it can potentially reduce the formation of amyloid-beta plaques in the brain.
Check Digit Verification of cas no
The CAS Registry Mumber 883442-46-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,3,4,4 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 883442-46:
(8*8)+(7*8)+(6*3)+(5*4)+(4*4)+(3*2)+(2*4)+(1*6)=194
194 % 10 = 4
So 883442-46-4 is a valid CAS Registry Number.
