88139-91-7

Basic information

• Product Name: 2-Hydroxymethyl-5-bromopyridine
• Synonyms: 2-HYDROXYMETHYL-5-BROMOPYRIDINE;(5-BROMOPYRID-2-YL)METHANOL;(5-BROMO-PYRIDIN-2-YL)-METHANOL;5-BROMO-2-HYDROXYMETHYLPYRIDINE;5-Bromo-2-hydroxymethylpyridin;(5-BROMO-PYRIDIN-2-YL)METHANOL (5-BROMO-2-HYDROXYMETHYLPYRIDINE);5-Bromo-2-pyridinemethanol;(5-Bromopyridin-2-yl)methanol ,98%
• CAS NO: 88139-91-7
• Molecular Formula: C₆H₆BrNO
• Molecular Weight: 188.02
• EINECS: 476-710-3
• Product Categories: blocks;Bromides;Pyridines;Pyridine;Building Blocks;Pyridine Series;Heterocycle-Pyridine series
• Mol File: 88139-91-7.mol
• Article Data: 43

Chemical Properties

• Melting Point: 59-60°C
• Boiling Point: 0°C
• Flash Point: 0°C
• Appearance: light yellow cryst.
• Density: 1.669 g/cm³
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 13.09±0.10(Predicted)
• CAS DataBase Reference: 2-Hydroxymethyl-5-bromopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxymethyl-5-bromopyridine(88139-91-7)
• EPA Substance Registry System: 2-Hydroxymethyl-5-bromopyridine(88139-91-7)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38-22
• Safety Statements: 22-26-36/37/39-36
• HazardClass: IRRITANT
• Hazardous Substances Data: 88139-91-7(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow Cryst

InChI:InChI=1/C6H6BrNO/c7-5-1-2-6(4-9)8-3-5/h1-3,9H,4H2

Upstream product

• 31181-74-5 (5-bromopyridin-2-yl)methyl acetate 
• 97483-77-7 2-Cyano-5-bromopyridine 
• 77199-09-8 5-bromo-pyridine-2-carboxylic acid ethyl ester 
• 29682-15-3 methyl 5-bromopicolinate 
• 30766-11-1 5-bromoisonicotinic acid 
• 110-91-8 morpholine 
• 31181-90-5 5-bromo-pyridine-2-carbaldehyde 
• 900186-89-2 C₂HF₃O₂*C₆H₆BrNO 
• 3430-13-5 5-bromo-2-methylpyridine 
• 109-06-8 α-picoline 
• 624-28-2 2,5-dibromopyridine 
• 900186-88-1 trifluoro-acetic acid 5-bromo-pyridin-2-ylmethyl ester 
• 68-12-2 N,N-dimethyl-formamide 
• 31181-64-3 5-bromo-2-methyl-pyridine-N-oxide 

Downstream Products

• 31181-90-5 5-bromo-pyridine-2-carbaldehyde 
• 1456882-12-4 5-(2,6-bis(trifluoromethyl)phenyl)-2-(((tert-butyldimethylsilyl)oxy)methyl)pyridine 
• 1456882-13-5 5-(2,6-bis(trifluoromethyl)phenyl)-2-(chloromethyl)pyridine 
• 1456882-14-6 (2S,2'S)-1,1'-bis((5-(2,6-bis(trifluoromethyl)phenyl)pyridin-2-yl)methyl)-2,2'-bipyrrolidine 
• 1456882-15-7 (2R,2’R)-1,1’-bis((5-(2,6-bis(trifluoromethyl)phenyl)pyridin-2-yl)methyl)-2,2’-bipyrrolidine 
• 1206967-79-4 tert-butyl 4-[2-(4-carboxy-3-fluorophenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate 
• 1206967-78-3 tert-butyl 4-[2-(4-ethoxycarbonyl-3-fluorophenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate 
• 1206967-77-2 5-[1-(5-Isopropyl-1,2,4-oxadiazol-3-yl)piperidin-4-yl]-2-(4-methanesulfonylphenoxymethyl)pyridine 
• 1206968-68-4 N-Hydroxy-4-[2-(4-methanesulfonylphenoxymethyl)-pyridin-5-yl]piperidin-1-carboxamidine 
• 1206968-67-3 4-[2-(4-methanesulfonylphenoxymethyl)pyridin-5-yl]piperidin-1-carbonitrile 
• 1206967-70-5 tert-butyl 4-[2-(4-methanesulfonylphenoxymethyl)-pyridin-5-yl]piperidine-1-carboxylate 
• 1206968-66-2 4-[2-(4-methanesulfonylphenoxymethyl)pyridin-5-yl]piperidine 
• 1206968-53-7 tert-Butyl 4-[2-(4-methanesulfonylphenylthiomethyl)-pyridin-5-yl]piperidine-1-carboxylate 
• 1206968-47-9 tert-butyl (E)-4-[2-[2-(4-methanesulfonylphenyl)vinyl]pyridin-5-yl]piperidine-1-carboxylate 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING)

The present invention relates to compounds of formula (I) and salts, stereoisomers, tautomers or N-oxides thereof that are useful as modulators of STING (Stimulator of Interferon Genes). The present invention further relates to the compounds of formula (I) for use as a medicament and to a pharmaceutical composition comprising said compounds.

SELECTIVE ESTROGEN RECEPTOR DOWNREGULATORS AND USES THEREOF

The invention relates to novel tetrahydroisoquinoline compounds that are selective estrogen receptor downregulators (SERDs). The present invention also relates to pharmaceutical compositions comprising one or more of the compounds as an active ingredient, and to the use of the compounds in the treatment of estrogen receptor (ER) mediated or dependent diseases or conditions, for example cancer such as breast cancer.

SUBSTITUTED OXAZOLE- AND THIAZOLE-BASED CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS II

The invention relates to oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.