869111-41-1 Usage
Uses
Used in Organic Synthesis:
CyclohexylMethyl N-tosyloxycarbaMate is used as a protecting group for amines to prevent unwanted reactions during the synthesis of complex organic molecules. Its stability and ease of removal under mild conditions make it an effective tool for amine protection and deprotection.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, CyclohexylMethyl N-tosyloxycarbaMate is used as a selective protecting agent for amine functional groups. This is crucial for the development of drugs where the selective protection and deprotection of amine groups can influence the pharmacological properties and activity of the compound.
Used in Drug Development:
CyclohexylMethyl N-tosyloxycarbaMate plays a significant role in drug development, where it is employed to protect amine groups during the synthesis of pharmaceutical compounds. Its ability to be easily removed under mild conditions allows for the precise control of amine exposure, which is essential for the synthesis of biologically active molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 869111-41-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,1,1 and 1 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 869111-41:
(8*8)+(7*6)+(6*9)+(5*1)+(4*1)+(3*1)+(2*4)+(1*1)=181
181 % 10 = 1
So 869111-41-1 is a valid CAS Registry Number.
869111-41-1Relevant articles and documents
N-tosyloxycarbamates as a source of metal nitrenes: Rhodium-catalyzed C-H insertion and aziridination reactions
Lebel, Helene,Huard, Kim,Lectard, Sylvain
, p. 14198 - 14199 (2007/10/03)
The rhodium-catalyzed decomposition of N-tosyloxycarbamates to generate metal nitrenes which undergo intramolecular C-H insertion or aziridination reaction is described. Aliphatic N-tosyloxycarbamates produce oxazolidinones with high yields and stereospecificity through insertion in benzylic, tertiary, and secondary C-H bonds. Intramolecular aziridination occurs with allylic N-tosyloxycarbamates to produce aziridines as single diastereomers. The reaction proceeds at room temperature using a rhodium catalyst and an excess of potassium carbonate and does not require the use of strong oxidant, such as hypervalent iodine reagents. A rhodium nitrene species is presumably involved, as both reactions are stereospecific. Copyright
