864924-26-5Relevant articles and documents
Stereochemical assignment of intermediates in the rifamycin biosynthetic pathway by precursor-directed biosynthesis
Hartung, Ingo V.,Rude, Mathew A.,Schnarr, Nathan A.,Hunziker, Daniel,Khosla, Chaitan
, p. 11202 - 11203 (2007/10/03)
Natural and semisynthetic rifamycins are clinically important inhibitors of bacterial DNA-dependent RNA polymerase. Although the polyketide-nonribosomal peptide origin of the naphthalene core of rifamycin B is well established, the absolute and relative c