863288-39-5

Basic information

• Product Name: methyl (E)-3-(5-fluoro-2-hydroxyphenyl)acrylate
• Synonyms: methyl (E)-3-(5-fluoro-2-hydroxyphenyl)acrylate
• CAS NO: 863288-39-5
• Molecular Weight: 196.178
• Mol File: 863288-39-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl (E)-3-(5-fluoro-2-hydroxyphenyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (E)-3-(5-fluoro-2-hydroxyphenyl)acrylate(863288-39-5)
• EPA Substance Registry System: methyl (E)-3-(5-fluoro-2-hydroxyphenyl)acrylate(863288-39-5)

Safety Data

• Hazardous Substances Data: 863288-39-5(Hazardous Substances Data)

Upstream product

• 347-54-6 5-fluoro-2-hydroxybenzaldehyde 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 371-41-5 4-Fluorophenol 

Downstream Products

• 936328-22-2 methyl (2E)-3-(5-fluoro-2-{[(2S)-2-methyloxiran-2-yl]methoxy}phenyl)acrylate 

Relevant articles and documents

Free radical scavenging and α-glucosidase inhibitory activity of (E)-methyl/ethyl-3-(2-hydroxyphenyl)acrylates

(E)-Methyl/ethyl-3-(2-hydroxyphenyl)acrylates 3a-x have been prepared by the reaction of salicylaldehydes 1a-l with Wittig reagents such as methyl (triphenylphosphoranylidene)acetate 2a and ethyl (triphenylphosphoranylidene)acetate 2b in dry DCM at room t

One-pot synthesis of ortho-hydroxycinnamate esters

Phenols are converted to salicylaldehydes with paraformaldehyde, MgCl 2-Et3N in THF, and subsequent treatment with methyl (triphenylphosphoranylidene)acetate gave the corresponding methyl ortho-hydroxycinnamate derivatives. The sequence is conveniently carried out as a one-pot procedure.