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851723-84-7

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  • 851723-84-7 Structure

  • Basic information

    1. Product Name: OC000459
    2. Synonyms: OC000459;2-(5-fluoro-2-Methyl-3-(quinolin- 2-ylMethyl)-1H-indol-1-yl)acetic acid;5-Fluoro-2-Methyl-3-quinolin-2-ylMethylindo-1-yl)-acetic(OC000459);[5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid;5-Fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indole-1-acetic acid;OC000495;(5-Fluoro-3-isoquinolin-3-ylMethyl-2-Methyl-indol-1-yl)-acetic acid;1H-Indole-1-acetic acid, 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-
    3. CAS NO:851723-84-7
    4. Molecular Formula: C21H17FN2O2
    5. Molecular Weight: 348.3702832
    6. EINECS: N/A
    7. Product Categories: Inhibitors
    8. Mol File: 851723-84-7.mol
    9. Article Data: 0

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 574.416 °C at 760 mmHg
    3. Flash Point: 301.196 °C
    4. Appearance: /
    5. Density: 1.29
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 4.08±0.10(Predicted)
    10. CAS DataBase Reference: OC000459(CAS DataBase Reference)
    11. NIST Chemistry Reference: OC000459(851723-84-7)
    12. EPA Substance Registry System: OC000459(851723-84-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 851723-84-7(Hazardous Substances Data)

851723-84-7 Usage

Description

OC000459 is a CRTH2 antagonist, a type of drug that targets the chemoattractant receptor-homologous molecule expressed on Th2 cells. It is a promising pharmaceutical candidate for the treatment of allergies.

Uses

Used in Allergy Treatment:
OC000459 is used as an allergy treatment to reduce nasal and ocular symptoms in subjects exposed to allergens. As a CRTH2 antagonist, it helps to alleviate the symptoms associated with allergic reactions by blocking the action of certain inflammatory mediators.

Check Digit Verification of cas no

The CAS Registry Mumber 851723-84-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,7,2 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 851723-84:
(8*8)+(7*5)+(6*1)+(5*7)+(4*2)+(3*3)+(2*8)+(1*4)=177
177 % 10 = 7
So 851723-84-7 is a valid CAS Registry Number.

851723-84-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid

1.2 Other means of identification

Product number -
Other names 2-[5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:851723-84-7 SDS

851723-84-7Upstream product

851723-84-7Downstream Products

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