851-78-5

Basic information

• Product Name: N-phenylsulfonyl-1,1-diphenylmethylamine
• Synonyms: N-phenylsulfonyl-1,1-diphenylmethylamine
• CAS NO: 851-78-5
• Molecular Weight: 323.415
• Mol File: 851-78-5.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: N-phenylsulfonyl-1,1-diphenylmethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenylsulfonyl-1,1-diphenylmethylamine(851-78-5)
• EPA Substance Registry System: N-phenylsulfonyl-1,1-diphenylmethylamine(851-78-5)

Safety Data

• Hazardous Substances Data: 851-78-5(Hazardous Substances Data)

Upstream product

• 98-10-2 benzenesulfonamide 
• 91-01-0 1,1-Diphenylmethanol 
• 100727-40-0 nitric acid benzhydryl ester 
• 13909-34-7 N-benzylidenephenylsulfonamide 
• 1623-99-0 phenyl sodium 
• 113548-13-3 N-(benzenesulfonyl)-3-phenyloxaziridine 
• 934-56-5 trimethyl(phenyl)stannane 
• 143-66-8 sodium tetraphenyl borate 
• 98-80-6 phenylboronic acid 
• 574-66-3 Benzophenone oxime 
• 21160-02-1 benzophenone O-acetyl oxime 
• 90-99-3 diphenylchloromethane 
• 776-74-9 Bromodiphenylmethane 
• 101-81-5 Diphenylmethane 

Relevant articles and documents

An efficient metal-free oxidative esterification and amination of benzyl C-H bond

An esterification and amination of benzylic C-H bonds was developed by using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) under metal- and iodide-free conditions. Both carboxylic acids and amines could be used as ideal coupling partners for the oxidati

Air-stable Bis(pentamethylcyclopentadienyl) Zirconium Perfluorooctanesulfonate as an Efficient and Recyclable Catalyst for the Synthesis of N-substituted Amides

Bis(pentamethylcyclopentadienyl) zirconium perfluorooctanesulfonate is an air-stable and water-tolerant Lewis acid. This complex exhibited good thermal stability and high solubility in polar organic solvents. The compound showed relatively strong acidity, with an acid strength of 0.8Ho≤3.3, and high catalytic efficiency for the synthesis of N-substituted amides via the reaction of carboxylic acids with amines, the Ritter reaction of nitriles with alcohols, and the amination of alcohols with amides. Moreover, the complex had good reusability. This catalytic system affords a simple and efficient way to synthesize N-substituted amides.

Selective catalytic Hofmann: N -alkylation of poor nucleophilic amines and amides with catalytic amounts of alkyl halides

Using only catalytic amounts of alkyl halides in the reactions of poor nucleophilic amines/amides and alcohols led to a selective Hofmann N-alkylation reaction catalytic in alkyl halides, providing a practical and efficient method for the practical synthesis of mono- or di-alkylated amines/amides in high selectivities. This new method avoids the use of large amounts of bases, alkyl halides, and solvents, and generates water as the only byproduct. Preliminary mechanistic studies showed that alkyl halides are key intermediates/catalysts regeneratable in the reaction cycle.