84942-40-5

Basic information

• Product Name: 5'-Chloro-2'-hydroxy-3'-nitroacetophenone
• Synonyms: TIMTEC-BB SBB005893;6-CHLORO-7-METHYLCHROMANONE;5-Chloro-3-nitro-2-hydroxyacetophenone;5-Chloro-2-hydroxy-3-nitroacet;2''-HYDROXY-3''-NITRO-5''-CHLOROACETOPHENONE;1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone;5'-Chloro-2'-hydroxy-3'-nitroacetophenone;5'-Chloro-2'-hydroxy
• CAS NO: 84942-40-5
• Molecular Formula: C₈H₆ClNO₄
• Molecular Weight: 215.59
• Product Categories: C7 to C8;Carbonyl Compounds;Ketones
• Mol File: 84942-40-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 132-135 °C(lit.)
• Boiling Point: 260.7 °C at 760 mmHg
• Flash Point: 111.5 °C
• Appearance: /
• Density: 1.505
• CAS DataBase Reference: 5'-Chloro-2'-hydroxy-3'-nitroacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-Chloro-2'-hydroxy-3'-nitroacetophenone(84942-40-5)
• EPA Substance Registry System: 5'-Chloro-2'-hydroxy-3'-nitroacetophenone(84942-40-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 84942-40-5(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
5'-Chloro-2'-hydroxy-3'-nitroacetophenone is used as a key intermediate for the synthesis of 6-chloro-8-nitro-4-oxo-4H-chromene-3-carbaldehyde, a compound with potential applications in various fields.
Used in Pharmaceutical Industry:
5'-Chloro-2'-hydroxy-3'-nitroacetophenone can be used as a building block for the development of new pharmaceutical compounds, given its unique functional groups and reactivity.
Used in Dye and Pigment Industry:
Due to its reactivity and functional groups, 5'-Chloro-2'-hydroxy-3'-nitroacetophenone can be used in the synthesis of dyes and pigments, contributing to the development of new colorants with improved properties.
Used in Material Science:
5'-Chloro-2'-hydroxy-3'-nitroacetophenone can be employed in the synthesis of new materials with specific properties, such as polymers, coatings, and adhesives, by taking advantage of its reactivity and functional groups.

Preparation

Preparation by reaction of nitric acid on 5-chloro-2- hydroxyacetophenone in acetic acid at r.t.

Upstream product

• 106-48-9 4-chloro-phenol 
• 876-27-7 4-chlorophenyl acetate 
• 1450-74-4 5-chloro-2-hydroxyacetophenone 

Downstream Products

• 1355198-81-0 2-hydroxy-5-chloro-3-nitroacetophenone isonicotinoylhydrazone 
• 1449688-63-4 C₂₀H₁₅ClFNO₆ 
• 1449688-69-0 C₁₈H₁₁ClFNO₆ 

Relevant articles and documents

Synthesis of hydrazones schiff bases and microbiological evaluation of lsonicotinoyl hydrazide with different acetophenone

A series of hydrazones Schiff bases compounds have been synthesized by reacting isonicotinoyl hydrazide with 2-hydroxy-5-chloro acetophenone, 2-hydroxy-5-methyl acetophenone, 2-hydroxy-5-carboxy acetophenone, 2,5-dihydroxy acetophenone, 2-hydroxy-5-chloro-4-methyl acetophenone, 2-hydroxy-5-chloro-3- nitro acetophenone, 2-hydroxy-5-methyl-3-nitro acetophenone and 2-hydroxy-5-bromo acetophenone. The Schiff bases have been evaluated for the antifungal and antibacterial activities.

Substituted alkylaryl ketones and methods of use as herbicides

Ring and side chain substituted alkylaryl ketones are useful in controlling the growth of germinating and seedling weed grasses and germinating and seedling broadleaf weeds.