849062-36-8

Basic information

• Product Name: 3-BROMO-5-METHYLPHENYLBORONIC ACID
• Synonyms: 3-BROMO-5-METHYLBENZENEBORONIC ACID;3-BROMO-5-METHYLPHENYLBORONIC ACID;AKOS BRN-0928;3-Bromo-5-methylbenzeneboronic acid 97%;Boronic acid,B-(3-broMo-5-Methylphenyl)-;3-Bromo-5-methylbenzeneboronicacid97%
• CAS NO: 849062-36-8
• Molecular Formula: C₇H₈BBrO₂
• Molecular Weight: 214.85
• Product Categories: blocks;BoronicAcids;Aryl;Boronic Acids;Boronic Acids and Derivatives;Boronic Acids
• Mol File: 849062-36-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 278-283 °C(lit.)
• Boiling Point: 351.805 °C at 760 mmHg
• Flash Point: 166.566 °C
• Appearance: /
• Density: 1.577 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.585
• Storage Temp.: Keep Cold
• PKA: 7.65±0.10(Predicted)
• CAS DataBase Reference: 3-BROMO-5-METHYLPHENYLBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-5-METHYLPHENYLBORONIC ACID(849062-36-8)
• EPA Substance Registry System: 3-BROMO-5-METHYLPHENYLBORONIC ACID(849062-36-8)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 849062-36-8(Hazardous Substances Data)

Usage

General Description

3-Bromo-5-methylphenylboronic acid is a chemical compound consisting of a boronic acid group attached to a phenyl ring containing a bromine and a methyl group. It is commonly used as a reagent in organic synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. It is also utilized in the development of pharmaceuticals, agrochemicals, and materials science. 3-BROMO-5-METHYLPHENYLBORONIC ACID is a valuable building block in the production of complex organic molecules and is known for its stability and versatility in various chemical reactions. Additionally, it is considered relatively non-toxic and non-hazardous, making it a popular choice in research and industrial applications.

InChI:InChI=1/C7H8BBrO2/c1-5-2-6(8(10)11)4-7(9)3-5/h2-4,10-11H,1H3

Upstream product

• 5419-55-6 Triisopropyl borate 
• 1611-92-3 3,5-dibromotoluene 
• 121-43-7 Trimethyl borate 

Downstream Products

• 52488-28-5 1-bromo-3-methyl-5-nitrobenzene 
• 29578-83-4 3-bromo-5-methoxytoluene 
• 74204-00-5 3-bromo-5-methylphenol 
• 116632-38-3 1-bromo-3-iodo-5-methylbenzene 

Relevant articles and documents

Preparation process for 3-methyl-5-methoxybenzenesulfonyl chloride

The invention discloses a preparation process for 3-methyl-5-methoxybenzenesulfonyl chloride. The process comprises the following steps: 3,5-dibromotoluene is used as an initial raw material, the 3,5-dibromotoluene is subjected to a boronic acidification reaction, thus 3-methyl-5-bromophenylboronic acid is obtained, the 3-methyl-5-bromophenylboronic acid is subjected to an oxidation reaction, thus 3-methyl-5-bromophenol is obtained, the 3-methyl-5-bromophenol is subjected to a substitution reaction, thus 3-methyl-5-bromoanisoles is obtained, the 3-methyl-5-bromoanisoles is subjected to sulfonation, thus 3-methyl-5-methoxybenzenesulfonate is obtained, the 3-methyl-5-methoxybenzenesulfonate is subjected to a substitution reaction, and therefore the objective compound 3-methyl-5-methoxybenzenesulfonyl chloride is obtained. According to the above route, the raw materials are easy to obtain, post-treatment is simple, convenient and easy to implement, a yield is relatively high, and the process has relatively-good application value.