848949-92-8

Basic information

• Product Name: ethyl 4-fluoro-4-Methyl-2-pent-4-enaMidopentanoate
• Synonyms: L-Leucine, 4-fluoro-N-(1-oxo-4-penten-1-yl)-, ethyl ester;(S)-ethyl 4-fluoro-4-methyl-2-(pent-4-enamido)pentanoate
• CAS NO: 848949-92-8
• Molecular Formula: C13H22FNO3
• Molecular Weight: 259.3170832
• Mol File: 848949-92-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 4-fluoro-4-Methyl-2-pent-4-enaMidopentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-fluoro-4-Methyl-2-pent-4-enaMidopentanoate(848949-92-8)
• EPA Substance Registry System: ethyl 4-fluoro-4-Methyl-2-pent-4-enaMidopentanoate(848949-92-8)

Safety Data

• Hazardous Substances Data: 848949-92-8(Hazardous Substances Data)

Upstream product

• 848949-86-0 ethyl-2-(diphenylmethyleneamino)-4-fluoro-4-methylpentanoate 
• 39716-58-0 pent-4-enoyl chloride 
• 591-80-0 pent-4-enoic acid 
• 1000995-94-7 C₁₃H₂₂FNO₃ 
• 848949-88-2 4-fluoro-4-methyl-2-pent-4-enoylamino-pentanoic acid 
• 64-17-5 ethanol 
• 848949-90-6 2-but-3-enyl-4-(2-fluoro-2-methyl-propyl)-4H-oxazol-5-one 

Downstream Products

• 848949-85-9 ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate sulfate salt 
• 1729-32-4 5-iodomethyl-dihydro-furan-2-one 
• 156047-39-1 ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate 
• 32730-32-8 5-bromomethyl-γ-butyrolactone 

Relevant articles and documents

Development of an improved immobilized CAL-B for the enzymatic resolution of a key intermediate to odanacatib

An immobilized form of Candida antarctica lipase B (CAL-B) has been developed with enhanced stability and activity compared to commercially available preparations. The immobilized CAL-B is more active, and 15 times more stable than the previously used preparation. This permits a continuous dynamic kinetic resolution process that is significantly less expensive than the original batch process, and with a 3-fold reduction in the process E-factor.

Process for preparing fluoroleucine alkyl esters

This invention relates to a stereoselective preparation of fluoroleucine alkyl esters.