84478-87-5

Basic information

• Product Name: 2-BROMO-4-FLUORO-5-NITROPHENOL
• Synonyms: 2-BROMO-4-FLUORO-5-NITROPHENOL;2-BROMO-4-FLURO-5-NITROPHENOL;4-Bromo-2-fluoro-5-hydroxynitrobenzene;Bromo-4-fluoro-5-nitrotoluene
• CAS NO: 84478-87-5
• Molecular Formula: C₆H₃BrFNO₃
• Molecular Weight: 236
• Product Categories: Phenol&Thiophenol&Mercaptan;API intermediates
• Mol File: 84478-87-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: 124-127℃
• Boiling Point: 302.379 °C at 760 mmHg
• Flash Point: 136.674 °C
• Appearance: Brown/Powder
• Density: 1.965 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.623
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 6.51±0.24(Predicted)
• CAS DataBase Reference: 2-BROMO-4-FLUORO-5-NITROPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-FLUORO-5-NITROPHENOL(84478-87-5)
• EPA Substance Registry System: 2-BROMO-4-FLUORO-5-NITROPHENOL(84478-87-5)

Safety Data

• Hazard Codes: Xi
• RIDADR: UN2811
• HazardClass: 6.1
• Hazardous Substances Data: 84478-87-5(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research and Development:
2-Bromo-4-Fluoro-5-Nitrophenol is used as a research compound for its unique chemical properties. It is employed in various chemical studies and experiments to understand its reactivity and potential applications in different fields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Bromo-4-Fluoro-5-Nitrophenol is used as an intermediate compound in the synthesis of various drugs. Its unique structure allows for the development of new drug molecules with potential therapeutic applications.
Used in Material Science:
2-Bromo-4-Fluoro-5-Nitrophenol is used as a component in the development of new materials with specific properties. Its reactivity and functional groups make it a valuable building block in the creation of advanced materials for various applications, such as in electronics or coatings.

InChI:InChI=1/C6H3BrFNO3/c7-3-1-4(8)5(9(11)12)2-6(3)10/h1-2,10H

Upstream product

• 496-69-5 2-bromo-4-fluoro-phenol 
• 371-41-5 4-Fluorophenol 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 84478-73-9 4-bromo-2-fluoro-5-hydroxyaniline 
• 84478-82-0 2-bromo-4-fluoro-5-nitrophenyl isopropyl ether 
• 1075700-83-2 6-{6-[2-(tert-butoxycarbonylamino)ethoxy]-2,3-difluorobenzyloxy}-3-fluoro-4-nitro-1-bromobenzene 
• 678969-88-5 5-fluoro-2-methoxy-4-nitrobenzaldehyde 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS

The present invention provides a compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof has an BET family protein inhibitory action, and is useful as an agent for the prophylaxis or treatment of autoimmune diseases and/or inflammatory diseases (e.g., rheumatoid arthritis, multiple sclerosis, idiopathic pulmonary fibrosis, psoriasis, atopic dermatitis, inflammatory bowel disease, Sjogren's syndrome, Behcet's disease, systemic lupus erythematosus etc.), cancer and the like.

FUSED HETEROCYCLIC DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE DERIVATIVE, AND USE OF THE COMPOSITION FOR MEDICAL PURPOSES

The present invention provides compounds useful as agents for the prevention or treatment of a sex hormone-dependent disease or the like. That is, the present invention provides fused heterocyclic derivatives represented by the following general formula (I), pharmaceutical compositions containing the same, medicinal uses thereof and the like. In the formula (I), rings A is 5-membered cyclic unsaturated hydrocarbon or 5-membered heteroaryl; RA is halogen, alkyl, alkenyl, alkynyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl, etc.; ring B is aryl or heteroaryl; RB is halogen, alkyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl, etc.; E1 and E2 are oxygen atom, etc.; U is single bond or alkylene; X is a group represented by Y, -O-(alkylene)-Y or -O-Z (in which Y is Z or amino substituted by Z, etc.; Z is cycloalkyl, heterocycloalkyl, aryl, heteroaryl, etc.

Condensed heterocylic compounds and herbicides containing them

Condensed heterocyclic compounds of general formula (I) wherein T is carbon or nitrogen; when T is carbon, then the bond between T and A is a double bond, the bond between A and Y is a single bond, and Y is oxygen, sulfur, or optionally substituted NH; or

Pyridazin-3-one derivatives, their use, and intermediates for their production

Novel hydrazones of formula [2] having the following structural formula are provided, which are useful intermediates to form active ingredients of herbicides, wherein R3 is hydrogen, alkyl, haloalkyl, or alkoxy alkyl; and Q is [Q-1], [Q-2], [Q-

Pyridazin-3-one derivatives, their use, and intermediates for their production

PCT No. PCT/JP96/02311 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1998 PCT Filed Aug. 19, 1996 PCT Pub. No. WO97/07104 PCT Pub. Date Feb. 27, 1997Novel pyridazin-3-one derivatives of formula [1] are provided, which are useful as active ingredie

Herbicidal 1-aryl-Δ2 -1,2,4-triazolin-5-ones

Novel aryltriazolinone compounds of the formula STR1 in which X is a chlorine or bromine atom and R is a radical selected from the group consisting of methyl, ethyl, 1-methylethyl, methoxymethyl, 2-methoxyethyl, 1-methyl-2-methoxyethyl, 2-propenyl, 2-prop

2-(2-Fluoro-4-halo-5-substituted phenyl) hydantoins and use

A herbicidal composition which comprises as an active ingredient a compound of the formula: STR1 wherein X is a chlorine atom or a bromine atom, Y is --CH2 --, --S-- or --SO2 -- and R is a C1 -C4 alkyl group, an allyl group or a propargyl group, and an inert carrier.

4-(2-Fluoro-4-halo-5-substituted phenyl)urazols, and their production and use

A condensed phenylurazol of the formula: STR1 wherein X is a chlorine atom or a bromine atom, Y and Z are each an oxygen atom or a sulfur atom and R is a C1 -C3 alkyl group, an allyl group or a propargyl group and n is an integer of 4 or 5, which is useful as a herbicide.

N-(2-Fluoro-4-halo-5-substituted phenyl) hydantoins

A composition comprising an N-(2-fluoro-4-halo-5-substituted phenyl) hydantoin of the formula: STR1 wherein X is a chlorine atom or a bromine atom and R1 and R2 are, same or different, each a C1 -C4 alkyl group, a cyclopropyl group, a C3 -C4 alkenyl group or a C3 -C4 alkynyl group and an inert carrier, which is useful as a herbicide.

Tetrahydrophthalimides, and their production and use

A compound of the formula: STR1 wherein X is a chlorine atom or a bromine atom, which is useful as a herbicide.