83104-85-2 Usage
Description
Glycine,N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[2-[[8-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-,(acetyloxy)methyl ester is a complex organic compound that is a derivative of Glycine. It is characterized by the presence of multiple acetyloxymethoxy and amino groups, as well as a quinolinyl moiety. Glycine,N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[2-[[8-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-,(acetyloxy)methyl ester is a cell-permeant acetoxymethyl ester, which allows it to be hydrolyzed by intracellular esterases to produce its active form.
Uses
Used in Biological Research:
Glycine,N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[2-[[8-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-,(acetyloxy)methyl ester is used as a fluorescent probe for the measurement of calcium in biological systems and for selected divalent cations. Its cell permeability and fluorescence properties make it a valuable tool for studying calcium signaling and dynamics in living cells.
Used in Calcium Imaging:
In the field of calcium imaging, this compound is used as a high affinity fluorescent calcium indicator. Upon binding to calcium, it exhibits a large shift in the UV absorption spectrum and a significant increase in fluorescence. This allows for the detection and quantification of calcium ions in cellular environments, which is crucial for understanding various cellular processes.
Used in Buffering Intracellular Calcium Transients:
Due to its high affinity for calcium and its ability to be used in loading concentrations up to 2 mM without serious toxic effects, Glycine,N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[2-[[8-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-,(acetyloxy)methyl ester can be used to buffer intracellular calcium transients. This application is particularly useful in studying the role of calcium in cell signaling and other physiological processes.
Used in Pharmaceutical Development:
Given its unique structure and properties, Glycine,N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[2-[[8-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-,(acetyloxy)methyl ester may also be utilized in the development of pharmaceuticals targeting calcium-related disorders or for the design of drugs that modulate calcium signaling pathways.
Used in Analytical Chemistry:
Glycine,N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[2-[[8-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-,(acetyloxy)methyl ester's fluorescence properties can be employed in analytical chemistry for the detection and quantification of calcium ions in various samples, including environmental, clinical, and industrial settings. This can aid in assessing the calcium content in different matrices and contribute to quality control measures.
Check Digit Verification of cas no
The CAS Registry Mumber 83104-85-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,1,0 and 4 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 83104-85:
(7*8)+(6*3)+(5*1)+(4*0)+(3*4)+(2*8)+(1*5)=112
112 % 10 = 2
So 83104-85-2 is a valid CAS Registry Number.
InChI:InChI=1/C38H43N3O18/c1-23-7-10-31(40(14-34(46)56-19-52-24(2)42)15-35(47)57-20-53-25(3)43)33(11-23)51-18-29-9-8-28-12-30(50-6)13-32(38(28)39-29)41(16-36(48)58-21-54-26(4)44)17-37(49)59-22-55-27(5)45/h7-13H,14-22H2,1-6H3
