830-50-2 Usage
Description
1-(PENTAFLUOROPHENYL)ETHANOL, 97 is a chemical compound with a purity of 97%, characterized by its colorless liquid state and molecular formula C8H5F5O. It features an aromatic pentafluorophenyl group attached to an ethyl alcohol functional group, which makes it a valuable building block in the synthesis of a variety of organic compounds and pharmaceuticals. Its unique structure allows it to participate in reactions that necessitate both a phenyl and an alcohol group, contributing to its versatility as a reagent for organic synthesis.
Uses
Used in Pharmaceutical Synthesis:
1-(PENTAFLUOROPHENYL)ETHANOL, 97 is used as a key intermediate in the pharmaceutical industry for the synthesis of various drugs. Its presence in the molecular structure facilitates the creation of new compounds with potential therapeutic applications.
Used in Organic Compound Synthesis:
In the field of organic chemistry, 1-(PENTAFLUOROPHENYL)ETHANOL, 97 is utilized as a building block for the synthesis of a range of organic compounds. Its ability to participate in reactions requiring both phenyl and alcohol groups makes it a valuable component in the development of new chemical entities.
Used in Fine Chemicals Production:
1-(PENTAFLUOROPHENYL)ETHANOL, 97 is employed as a versatile reagent in the preparation of intermediates for fine chemicals. Its unique properties allow for the creation of high-quality specialty chemicals used across various industries.
Used in Research and Development:
In the realm of scientific research and development, 1-(PENTAFLUOROPHENYL)ETHANOL, 97 serves as a crucial component in experiments and the development of new methodologies, contributing to advancements in organic synthesis and related fields.
Check Digit Verification of cas no
The CAS Registry Mumber 830-50-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,3 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 830-50:
(5*8)+(4*3)+(3*0)+(2*5)+(1*0)=62
62 % 10 = 2
So 830-50-2 is a valid CAS Registry Number.
830-50-2Relevant articles and documents
Decarboxylative Polyfluoroarylation of Alkylcarboxylic Acids
Sun, Xiang,Ritter, Tobias
supporting information, p. 10557 - 10562 (2021/04/05)
Polyfluoroarenes are useful building blocks in several areas such as drug discovery, materials, and crop protection. Herein, we report the first polyfluoroarylation of aliphatic carboxylic acids via photoredox decarboxylation. The method proceeds with bro
Asymmetric Hydrogenation of Aryl Perfluoroalkyl Ketones Catalyzed by Rhodium(III) Monohydride Complexes Bearing Josiphos Ligands
Brüning, Fabian,Nagae, Haruki,K?ch, Daniel,Mashima, Kazushi,Togni, Antonio
supporting information, p. 10818 - 10822 (2019/07/31)
The asymmetric hydrogenation of 2,2,2-trifluoroacetophenones and aryl perfluoroalkyl ketones was developed using a unique, well-defined chloride-bridged dinuclear rhodium(III) complex bearing Josiphos-type diphosphine ligands. These complexes were prepared from [RhCl(cod)]2, Josiphos ligands, and hydrochloric acid. As catalyst precursors, they allow for the efficient and enantioselective synthesis (up to 99 % ee) of chiral secondary alcohols with perfluoroalkyl groups. This system does not require an activating base for the hydrogenation of 2,2,2-trifluoroacetophenones. Additionally, the enantioselective C=O hydrogenations of 2-phenyl-3-(haloacetyl)-indoles, a class of privileged structures in medicinal chemistry, is reported for the first time.
C(sp2)-F Oxidative Addition of Fluorinated Aryl Ketones by iPrPCPIr
Wilklow-Marnell, Miles,Brennessel, William W.,Jones, William D.
, p. 3125 - 3134 (2017/09/05)
The reaction of iPrPCPIrH4 (iPrPCP = κ3-2,6-C6H3(CH2P(iPr)2)2) with ≥2 equiv of 2,3,4,5,6-pentafluoroacetophenone (AP-F5) in aromatic solvents at