82938-20-3

Basic information

• Product Name: 1-(4-METHOXYPHENYL)-3-METHYLBUTAN-1-ONE
• Synonyms: 1-(4-METHOXYPHENYL)-3-METHYLBUTAN-1-ONE;1-(4-METHOXYPHENYL)-3-METHYLBUTAN-1-ONE(WXG01592)
• CAS NO: 82938-20-3
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.25
• Mol File: 82938-20-3.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-METHOXYPHENYL)-3-METHYLBUTAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-METHOXYPHENYL)-3-METHYLBUTAN-1-ONE(82938-20-3)
• EPA Substance Registry System: 1-(4-METHOXYPHENYL)-3-METHYLBUTAN-1-ONE(82938-20-3)

Safety Data

• Hazardous Substances Data: 82938-20-3(Hazardous Substances Data)

Usage

Physical state

Yellow liquid

Odor

Floral, spicy

Industry use

Fragrance and flavor industry as a scent enhancer and fixative

Additional uses

Production of cosmetic and personal care products, synthesis of other organic compounds

Potential applications

Pharmaceuticals and agrochemicals

Safety concerns

Flammability, skin and eye irritant properties

Handling and storage

Proper handling and storage required due to safety concerns

Upstream product

• 503-74-2 3-methylbutyric acid 
• 100-66-3 methoxybenzene 
• 1468-39-9 Isovaleric anhydride 
• 108-12-3 isopentanoyl chloride 
• 78-77-3 Isobutyl bromide 
• 696-62-8 para-iodoanisole 
• 107035-97-2 2,5-dimethyl-3-(1-methylethyl)-5-hexen-3-ol 
• 123-11-5 4-methoxy-benzaldehyde 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 590-86-3 isovaleraldehyde 
• 71370-05-3 4-methyl-2-phenylpent-4-en-2-ol 
• 5674-02-2 2-methylpropylmagnesium chloride 
• 874-90-8 4-methoxybenzonitrile 
• 623-12-1 4-chloromethoxybenzene 

Downstream Products

• 33810-04-7 1-(4-methoxyphenyl)-3-methylbutane-1,2-dione 
• 84958-14-5 2-[(E)-3-(4-Methoxy-phenyl)-5-methyl-hex-2-enyl]-2-methyl-cyclopentane-1,3-dione 
• 82938-21-4 Cyano-2-(p-methoxyphenyl)-4-methyl-pent-1-ene 
• 32097-05-5 4-methoxy-β,β-dimethylacrylophenone 
• 34887-83-7 1-(4-hydroxyphenyl)-3-methylbutan-1-one 
• 82938-25-8 N-<3-(p-Methoxyphenyl)-5-methylhex-2-enyl>succinimide 
• 82938-27-0 N-<3-(p-Methoxyphenyl)-5-methylhex-2-enyl>-5-ethoxy-2-pyrrolidinone 
• 78349-20-9 (1R,2R,5R)-2-Isobutyl-2-(4-methoxy-phenyl)-5-methyl-bicyclo[3.2.1]octane-6,8-dione 
• 78349-27-6 (1S,2R,5S)-2-Isobutyl-2-(4-methoxy-phenyl)-5-methyl-bicyclo[3.2.1]octane-6,8-dione 
• 100757-90-2 1-(p-methoxyphenyl)-3-methyl-1-butanol 
• 1381862-15-2 (S)-2-isopropyl-1-(4-methoxyphenyl)pent-4-en-1-one 
• 1381862-29-8 C₁₄H₁₈O₃ 
• 1381862-22-1 C₁₆H₂₀O₄ 
• 1430321-36-0 C₁₉H₂₃N₃O₂ 

Relevant articles and documents

Discovery of Novel 3-Amino-4-alkoxyphenylketones as PDE4 Inhibitors with Improved Oral Bioavailability and Safety against Spatial Memory Impairments

To realize PDE4 inhibitors with good developmental potentiality for the treatment of dementia, structure-based optimizations of lead compound FCPR03 resulted in novel aminophenylketones 9c and 9H with low nanomolar potency, which displayed comparable acti

Selective catalytic synthesis of α-alkylated ketones and β-disubstituted ketones via acceptorless dehydrogenative cross-coupling of alcohols

Herein, a phosphine-free pincer ruthenium(III) catalyzed β-alkylation of secondary alcohols with primary alcohols to α-alkylated ketones and two different secondary alcohols to β-branched ketones are reported. Notably, this transformation is environmentally benign and atom efficient with H2O and H2 gas as the only byproducts. The protocol is extended to gram-scale reaction and for functionalization of complex vitamin E and cholesterol derivatives.

Aminophenone compounds as well as preparation method and application thereof

The invention belongs to the technical field of medicinal chemistry, and particularly relates to aminophenone compounds as well as a preparation method and application thereof. The aminophenone compounds provided by the invention have a good inhibition effect on PDE4, also have good bioavailability, can be applied to preparation of drugs for treating PDE4-related diseases, and increase the optionsof drugs for treating PDE4-related diseases; and the effect of a part of the aminophenone compounds is equivalent to the effect of positive drugs, and the aminophenone compounds have good developmentpotential.