82830-53-3 Usage
Description
(±) DOI, also known as 2,5-dimethoxy-4-iodoamphetamine, is a psychoactive phenethylamine compound that acts as a potent and selective agonist for the serotonin 5-HT2A receptor. It is known for its hallucinogenic effects in humans and has been a subject of research for its potential therapeutic applications in mental health conditions, as well as for understanding the mechanisms of psychedelic drugs. However, its recreational use raises concerns due to its potential for abuse, leading to its classification as a Schedule I controlled substance in the United States.
Uses
Used in Pharmaceutical Research:
(±) DOI is used as a research compound for studying the serotonin 5-HT2A receptor's role in various mental health conditions, including depression and anxiety. Its agonistic properties allow scientists to explore the receptor's function and potential therapeutic targets.
Used in Understanding Psychedelic Mechanisms:
(±) DOI is utilized as a model compound to investigate the mechanisms of action of psychedelic drugs. Its selective binding to the 5-HT2A receptor provides insights into the neurobiological effects of hallucinogens and their potential therapeutic applications.
Used in Drug Development:
Although (±) DOI itself is not approved for medical use, its research contributes to the development of new drugs targeting the serotonin 5-HT2A receptor. Understanding its interactions with the receptor may lead to the creation of safer and more effective treatments for mental health disorders.
Used in Forensic Toxicology:
(±) DOI's classification as a Schedule I controlled substance necessitates its analysis in forensic toxicology. It is used for identifying and quantifying the presence of this substance in biological samples, such as blood or urine, to determine cases of abuse or illegal distribution.
Check Digit Verification of cas no
The CAS Registry Mumber 82830-53-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,8,3 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 82830-53:
(7*8)+(6*2)+(5*8)+(4*3)+(3*0)+(2*5)+(1*3)=133
133 % 10 = 3
So 82830-53-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3
82830-53-3Relevant articles and documents
Iodination of methoxyamphetamines with iodine and silver sulfate
Sy
, p. 6223 - 6224 (2007/10/02)
Iodination of methoxyamphetamines with iodine/silver sulfate at room temperature gives iodometyoxyamphetamines in good yield.
