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82419-52-1

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  • OFLOXACIN RELATED COMPOUND A (25 MG) ((RS)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-10-(PIPERA-ZIN-1 -YL)-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID)

    Cas No: 82419-52-1

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  • TaiChem Taizhou Limited
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  • 99% up by HPLC OFLOXACIN RELATED COMPOUND A (25 MG) ((RS)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-10-(PIPERA-ZIN-1 -YL)-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID) 82419-52-1

    Cas No: 82419-52-1

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  • Sinoway Industrial Co., Ltd.
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  • Ofloxacin Related Compound A (25 mg) (9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid)

    Cas No: 82419-52-1

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  • Henan Allgreen Chemical Co.,Ltd
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  • OFLOXACIN RELATED COMPOUND A (25 MG) ((RS)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-10-(PIPERA-ZIN-1 -YL)-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID)

    Cas No: 82419-52-1

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  • ZHEJIANG JIUZHOU CHEM CO.,LTD
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82419-52-1 Usage

Description

OFLOXACIN RELATED COMPOUND A (25 MG) ((RS)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-10-(PIPERA-ZIN-1 -YL)-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID) is a metabolite of Ofloxacin, a fluorinated quinolone antibacterial agent. It is characterized by its unique chemical structure, which includes a fluorine atom, a dihydro-dihydroxy-methyl group, a 7-oxo group, and a piperazinyl group attached to a pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid moiety.

Uses

Used in Pharmaceutical Industry:
OFLOXACIN RELATED COMPOUND A (25 MG) ((RS)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-10-(PIPERA-ZIN-1 -YL)-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID) is used as an impurity in the synthesis and manufacturing process of Ofloxacin, a widely used fluoroquinolone antibiotic. It plays a crucial role in ensuring the quality, safety, and efficacy of the final drug product by serving as a reference compound for quality control and regulatory compliance.
Additionally, as a metabolite of Ofloxacin, it may also be used in research and development for understanding the pharmacokinetics, metabolism, and potential side effects of the parent drug, Ofloxacin. This knowledge can contribute to the optimization of drug formulations, dosing regimens, and the development of new antimicrobial agents with improved safety and efficacy profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 82419-52-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,4,1 and 9 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 82419-52:
(7*8)+(6*2)+(5*4)+(4*1)+(3*9)+(2*5)+(1*2)=131
131 % 10 = 1
So 82419-52-1 is a valid CAS Registry Number.

82419-52-1 Well-known Company Product Price

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  • Sigma-Aldrich

  • (O0120050)  Ofloxacin impurity E  European Pharmacopoeia (EP) Reference Standard

  • 82419-52-1

  • O0120050

  • 1,880.19CNY

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  • USP

  • (1478119)  Ofloxacin Related Compound A  United States Pharmacopeia (USP) Reference Standard

  • 82419-52-1

  • 1478119-25MG

  • 14,578.20CNY

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82419-52-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-Demethylofloxacin

1.2 Other means of identification

Product number -
Other names Ofloxacin related compound A

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:82419-52-1 SDS

82419-52-1Relevant articles and documents

Nano-Fe3 O4@ZrO2-SO3 H as highly efficient recyclable catalyst for the green synthesis of fluoroquinolones

Nakhaei, Ahmad,Ramezani, Shirin,Shams-Najafi, Sayyed Jalal,Farsinejad, Sadaf

, p. 739 - 746 (2018/09/26)

Nano-Fe3 O4 @ZrO2-SO3 H (n-FZSA), was utilized as a magnetic catalyst for the synthesis of various fluoroquinolone compounds. These compounds were prepared by the direct amination of 7-halo-6-fluoroquinolone-3-carboxylic acids with piperazine derivatives and (4aR,7aR)-octahydro-1H-pyrrolo[3,4-b] pyridine in water. The results showed that n-FZSA exhibited high catalytic activity towards the synthesis of fluoroquinolone derivatives, giving the desired products in high yields. Furthermore, the catalyst was recyclable and could be used at least seven times without any discernible loss in its catalytic activity. Overall, this new catalytic method for the synthesis of fluoroquinolone derivatives provides rapid access to the desired compounds in refluxing water following a simple work-up procedure, and avoids the use of organic solvents.

Conventional and microwave-assisted synthesis of quinolone carboxylic acid derivatives

Mirzaie,Lari,Vahedi,Hakimi

, p. 2865 - 2869 (2017/03/22)

Various antibacterial fluoroquinolone compounds are synthesized by the direct amination of 7-halo-6-fluoroquinolone-3-carboxylic acids with a variety of piperazine derivatives and (4aR,7aR)-octahydro-1H-pyrrolo[3,4-b]pyridine using microwave under different reaction conditions. Solvent free high yield microwave synthesis of antibacterial fluoroquinolone compounds is convenient, rapid and environmentally friendly method.

Microwave assisted amination of quinolone carboxylic acids: An expeditious synthesis of fluoroquinolone antibacterials

Reddy,Baskaran

, p. 6775 - 6777 (2007/10/03)

A facile amination of quinolone carboxylic acids to fluoroquinolone antibacterials under microwave irradiation is described.

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