82196-88-1 Usage
Description
Chrysomycin A, a major analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces, is a potent compound with a vinyl group in the 8-position. It is considered the most potent analogue of the complex and is believed to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomycin A exhibits a potent antibacterial, antifungal, antiviral, and antitumor profile, with recent research suggesting its potential as a photoactivated cross-linker of DNA to histones.
Uses
Used in Pharmaceutical Industry:
Chrysomycin A is used as an antitumor agent for its potent inhibitory effects on the catalytic activity of human topoisomerase II, playing a crucial role in the development of cancer treatment.
Used in Antibacterial Applications:
Chrysomycin A is used as an antibacterial agent, effective against various bacterial strains, making it a valuable component in the fight against bacterial infections.
Used in Antifungal Applications:
Chrysomycin A is used as an antifungal agent, helping to combat fungal infections and contributing to the development of antifungal medications.
Used in Antiviral Applications:
Chrysomycin A is used as an antiviral agent, exhibiting potent activity against various viral strains, which can be instrumental in the creation of antiviral treatments.
Used in DNA Research:
Chrysomycin A is used as a photoactivated cross-linker of DNA to histones, which can aid in understanding the interactions between DNA and proteins, potentially leading to advancements in genetic research and medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 82196-88-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,1,9 and 6 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 82196-88:
(7*8)+(6*2)+(5*1)+(4*9)+(3*6)+(2*8)+(1*8)=151
151 % 10 = 1
So 82196-88-1 is a valid CAS Registry Number.
InChI:InChI=1/C28H28O9/c1-6-13-9-16-20(18(10-13)34-4)15-11-19(35-5)22-17(29)8-7-14(21(22)23(15)37-27(16)32)24-26(31)28(3,33)25(30)12(2)36-24/h6-12,24-26,29-31,33H,1H2,2-5H3/t12-,24+,25+,26+,28-/m1/s1
82196-88-1Relevant articles and documents
Anti-tuberculosis compound and synthesis method and application thereof
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, (2018/04/21)
The invention relates to an anti-tuberculosis compound with a general structural formula I shown in the description. The compound shows high inhibitory activity on mycobacterium tuberculosis. The invention further relates to a synthesis method of the anti-tuberculosis compound. In the method, a chemical total synthesis route is adopted; the convergent synthesis route is applicable to chemical synthesis of compounds of similar structures and related derivatives and opens up broad development space of new anti-tuberculosis drugs.