820-71-3Relevant articles and documents
METHOD FOR PRODUCING 1-ACYLOXY-2-METHYL-2-PROPENE
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Paragraph 0101-0104; 0107-0112, (2021/09/26)
A method for producing a 1-acyloxy-2-methyl-2-propene represented by the following general formula (II), including reacting a carboxylic acid represented by the following general formula (I), isobutylene, and oxygen, in the presence of a catalyst, in a liquid phase, with an amount of the isobutylene used of more than 1 mol and 50 mol or less per 1 mol of the carboxylic acid.
Method for preparing methallyl alcohol by using in-situ generated Cu (I) catalyst
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Paragraph 0026-0029, (2020/06/16)
The invention relates to a method for preparing methallyl alcohol by using an in-situ generated Cu (I) catalyst, which comprises the following steps: (1) dissolving a bivalent copper salt in water, adding a reducing organic matter, stirring, and dropwisely adding an obtained mixture into a methallyl alcohol preparation system; or (2) in themethallyl alcohol preparation system, adding thebivalent copper salt, then dropwise adding a reduced organic matter aqueous solution, and carrying out a catalytic reaction; or (3) in themethylallyl alcohol preparation system, adding a reduced organic matteraqueous solution, then dropwise adding a bivalent copper salt aqueous solution, and carrying out a catalytic reaction; or (4) mixing asolid bivalent copper salt with asolid reduced organic matter in proportion, adding an obtained mixture into themethallyl alcohol preparation system in batches, and carrying out catalytic reaction. The reaction system has the characteristics of high activity and high selectivity, can significantly improvethe conversion rate and selectivity of methylallyl alcohol, reducethe generation of by-product methylallyl ether, significantly reduces the synthesis cost by replacing monovalent copper with bivalent copper, and improve the market competitiveness.
Palladium-Catalyzed Asymmetric Allylic Alkylation of 4-Substituted Isoxazolidin-5-ones: Straightforward Access to β2,2-Amino Acids
Nascimento de Oliveira, Marllon,Arseniyadis, Stellios,Cossy, Janine
supporting information, p. 4810 - 4814 (2018/03/21)
We report here an unprecedented and highly enantioselective palladium-catalyzed allylic alkylation applied to 4-substituted isoxazolidin-5-ones. Ultimately, the process provides a straightforward access to β2,2-amino acids bearing an all-carbon quaternary stereogenic center in great yields and a high degree of enantioselectivity.