81060-96-0Relevant articles and documents
A Route from 1,1,1,3-Tetrachloro-3-phenylpropane to Ethynyl Phenyl Ketone Involving Elimination of Hydrogen Chloride and 1,3-Proton Transfer
Akiyama, Takeo,Yoshida, Yasuki,Hanawa, Tokiko,Sugimori, Akira
, p. 1795 - 1798 (2007/10/02)
The treatment of 1,1,1,3-tetrachloro-3-phenylpropane with alkali in ethanol affords ethynyl phenyl ketone and its acetal in good yields.This reaction proceeds through the elimination of hydrogen chloride and an efficient 1,3-proton transfer catalyzed by base.Ethyl cinnamate is obtained in only 2percent yield.