797055-37-9

Basic information

• Product Name: Spiro[4.5]dec-6-ene-2-carboxylic acid, 6,10-dimethyl-, methyl ester, (5R,10R)-rel- (9CI)
• Synonyms: Spiro[4.5]dec-6-ene-2-carboxylic acid, 6,10-dimethyl-, methyl ester, (5R,10R)-rel- (9CI)
• CAS NO: 797055-37-9
• Molecular Formula: C14H22O2
• Molecular Weight: 222.32328
• Product Categories: METHYL
• Mol File: 797055-37-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Spiro[4.5]dec-6-ene-2-carboxylic acid, 6,10-dimethyl-, methyl ester, (5R,10R)-rel- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[4.5]dec-6-ene-2-carboxylic acid, 6,10-dimethyl-, methyl ester, (5R,10R)-rel- (9CI)(797055-37-9)
• EPA Substance Registry System: Spiro[4.5]dec-6-ene-2-carboxylic acid, 6,10-dimethyl-, methyl ester, (5R,10R)-rel- (9CI)(797055-37-9)

Safety Data

• Hazardous Substances Data: 797055-37-9(Hazardous Substances Data)

Upstream product

• 121741-13-7 6-Hydroxy-6,10-dimethyl-spiro[4.5]decane-2-carboxylic acid methyl ester 
• 18444-84-3 (5S^*,10R^*)-6,10-dimethylspiro<4.5>dec-6-en-2-one 
• 186581-53-3 diazomethane 
• 81346-20-5 (2RS,5R^*,10R^*)-6,10-dimethylspiro<4.5>dec-6-ene-2-carboxylic acid 
• 121840-75-3 6-Methyl-10-methylene-spiro[4.5]decane-2-carboxylic acid methyl ester 
• 155528-07-7 (+)-(3R,4E)-3-(tert-butyldimethylsilyloxy)hex-4-enal 
• 120-92-3 cyclopentanone 
• 928203-31-0 6-(tert-butyl-dimethyl-silanyloxy)-10-methyl-spiro[4.5]dec-1-ene-2-carboxylic acid methyl ester 
• 928203-27-4 6-(tert-butyl-dimethyl-silanyloxy)-10-methyl-spiro[4.5]decan-1-one 
• 928203-22-9 2-[3-(tert-butyl-dimethyl-silanyloxy)-hex-4-enoyl]-cyclopentanone 
• 928203-21-8 2-[3-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-hex-4-enyl]-cyclopentanone 
• 928203-26-3 10-(tert-butyl-dimethyl-silanyloxy)-6-methyl-spiro[4.5]dec-7-en-1-one 
• 928203-25-2 tert-butyl-dimethyl-(2-propenyl-2,3,4,5,6,7-hexahydro-cyclopenta[b]pyran-4-yloxy)-silane 
• 928203-32-1 6-hydroxy-10-methyl-spiro[4.5]dec-1-ene-2-carboxylic acid methyl ester 

Relevant articles and documents

Claisen rearrangement strategy in alkenyl dihydropyran leading to total synthesis of (+)-α-vetispirene and (-)-agarospirol

Total synthesis of (+)-α-vetispirene and (-)-agarospirol based on a Claisen rearrangement has been achieved. This is the first example of a Claisen rearrangement in an enantio-enriched alkenyl bicyclic dihydropyran system with perfect asymmetric transmission. Copyright

Connective synthesis of spirovetivanes: Total synthesis of (±)-agarospirol, (±)-hinesol and (±)-α-vetispirene

A concise, connective synthesis of naturally occurring spirovetivanes 1 and 3, in racemic form, is presented. This novel approach involves the efficient assembly of the advanced intermediate 12 through a unique spiroannulation protocol. Wiley-VCH Verlag GmbH & Co. KGaA1 69451 Weinheim, Germany, 2004.

Synthesis based on cyclohexadienes. Part 21. Total synthesis of (±)-hinesol and (±)-10-epi-hinesol

An efficient strategy for the construction of the spiro[4.5]decane and eremane systems is described which involves an acid-catalysed rearrangement of an endo alcohol, followed by an oxidative cleavage resulting in the generation of a spiro-system, as the key step. This methodology is extended to the total synthesis of (±)-hinesol and (±)-10-epi-hinesol 2.