Welcome to LookChem.com Sign In|Join Free

CAS

  • or

79660-72-3

Post Buying Request

79660-72-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

79660-72-3 Usage

Description

Fleroxacin is a once-daily trifluoroquinolone antibacterial agent that is structurally related to norfloxacin. It is available in both oral and intravenous formulations and is known for its longer serum half-life of 9-12 hours compared to other drugs in its class, such as ciprofloxacin, enoxacin, and norfloxacin.

Uses

Used in Antibacterial Applications:
Fleroxacin is used as an antibiotic for the treatment of various bacterial infections, including gonorrhea, bacterial enteritis, chronic bronchitis, and urinary tract infections. Its longer serum half-life allows for once-daily dosing, making it a convenient option for patients.
Used in Pharmaceutical Industry:
Fleroxacin is used as a broad-spectrum antibiotic in the pharmaceutical industry for the development of medications to combat a wide range of bacterial infections. Its unique structural properties and extended half-life make it a valuable asset in the fight against antibiotic-resistant bacteria.

Manufacturing Process

6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4- oxoquinoline-3-carboxylic acid hydrochloride:A mixed solution of 1-methylpiperazine (0.34 g) and pyridine (3 ml) was added to 6,7,8-trifluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxoquinoline-3- carboxylic acid (0.12 g) and heated to reflux for 6 hours. After the solvent evaporated and cooled, the residue was adjusted to pH 1 with aqueous hydrochloric acid. The cooled mixture was filtered off and the solid recrystallized from water to give 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7- (4-methyl-1-piperazinyl)-4-oxoquinoline-3-carboxylic acid hydrochloride (0.08 g), melting point 269-271°C (decomp.).

Therapeutic Function

Antibacterial

Check Digit Verification of cas no

The CAS Registry Mumber 79660-72-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,6,6 and 0 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 79660-72:
(7*7)+(6*9)+(5*6)+(4*6)+(3*0)+(2*7)+(1*2)=173
173 % 10 = 3
So 79660-72-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H18F3N3O3/c1-21-4-6-22(7-5-21)15-12(19)8-10-14(13(15)20)23(3-2-18)9-11(16(10)24)17(25)26/h8-9H,2-7H2,1H3,(H,25,26)

79660-72-3 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • TCI America

  • (F0646)  Fleroxacin  >98.0%(T)

  • 79660-72-3

  • 5g

  • 990.00CNY

  • Detail
  • TCI America

  • (F0646)  Fleroxacin  >98.0%(T)

  • 79660-72-3

  • 25g

  • 3,450.00CNY

  • Detail

79660-72-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Fleroxacin

1.2 Other means of identification

Product number -
Other names hyl-1-piperazinyl)-4-oxo

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:79660-72-3 SDS

79660-72-3Relevant articles and documents

NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES

-

Page/Page column 6; 8-9, (2009/04/24)

The invention relates to a method of preparation of fluoroquinolones of formula (I) from compounds of formula (II): in which R1, R2, R3, R4, R5, R6, R7, and X are as defined in Claim 1.

A process for the preparation of quinoline carboxylic acid derivatives

-

, (2008/06/13)

-

Quinoline carboxylic acid derivatives and process for the preparation

-

, (2008/06/13)

This invention relates to new compounds of value as antibacterial agent. More particularly, it relates to quinoline carboxylic acid derivatives, the hydrates and the salts thereof.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 79660-72-3