79309-61-8

Basic information

• Product Name: methyl 2-(4-bromophenyl)-2-methoxyacetate
• CAS NO: 79309-61-8
• Molecular Weight: 259.1
• Mol File: 79309-61-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 2-(4-bromophenyl)-2-methoxyacetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(4-bromophenyl)-2-methoxyacetate(79309-61-8)
• EPA Substance Registry System: methyl 2-(4-bromophenyl)-2-methoxyacetate(79309-61-8)

Safety Data

• Hazardous Substances Data: 79309-61-8(Hazardous Substances Data)

Upstream product

• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 14062-25-0 Ethyl 4-bromophenylacetate 
• 124-41-4 sodium methylate 
• 99-90-1 para-bromoacetophenone 
• 149-73-5 trimethyl orthoformate 
• 264881-99-4 methyl 2-(4-bromophenyl)-2-diazoacetate 
• 67-56-1 methanol 
• 41841-16-1 (4-bromo-phenyl)-acetic acid methyl ester 

Relevant articles and documents

Silica-supported HClO4 promotes catalytic solvent- and metal-free O-H insertion reactions with diazo compounds

Solvent-free O-H insertion reactions in the presence of diazo carbonyl compounds were carried-out in very mild conditions. Unlike the traditional metal-catalysed version, employing rhodium acetate dimer, this method uses eco-friendly silica-supported HClO4 as the catalyst. Only 0.3 mol% of this Br?nsted acid catalyst, that can also be recycled several times, is necessary to guarantee very good yields (up to 97%) in the O-H insertion reactions. Reaction set-up is simple and permitted the preparation of forty-three α-hydroxy and α-alkoxy esters/ketones in just 1 h and at room temperature.

Hypervalent Iodine Oxidation of Aryl Methyl Ketones: A Convenient Route to Methyl α-Methoxyarylacetates

Hypervalent iodine oxidation of aryl methyl ketones using two equivalents of iodosobenzene diacetate leads to 1,2-aryl migration followed by solvohyperiodination to yield the corresponding methyl α-methoxyarylacetates.