7776-05-8Relevant articles and documents
CYP267A1 and CYP267B1 from sorangium cellulosum so ce56 are highly versatile drug metabolizers
Kern, Fredy,Khatri, Yogan,Litzenburger, Martin,Bernhardt, Rita
, p. 495 - 504 (2016/04/05)
The guidelines of the Food and Drug Administration and International Conference on Harmonization have highlighted the importance of drug metabolites in clinical trials. As a result, an authentic source for their production is of great interest, both for t
Analytical studies and application of reaction of promazine and thioridazine hydrochlorides with some oxidants
Puzanowska-Tarasiewicz, Helena,Karpinska, Joanna
, p. 409 - 415 (2007/10/03)
The run and analytical application of oxidation reaction of promazine (PM) and thioridazine (TR) hydrochlorides with iron(III) and ferrocyanide(III) are described. The coloured products of oxidation absorb at 512 nm for promazine and 634 nm for thioridazine. This property is a basis of a rapid, accurate and sensitive spectrophotometric method for determination of these phenothiazines. The elaborated methods allow to determine 3-28 μgPM/ml in Fe(III)-PM and 2-11 μgPM/ml in [Fe(CN)6]3 - PM systems, 2.5-22 μgTR/ml in the Fe(III)-TR and 4-16 μgTR/ml in [Fe(CN)6]3- - TR systems.