7645-81-0 Usage
Uses
1-(4-sec-Butylphenyl)ethanone is a useful synthetic intermediate in the synthesis of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
Check Digit Verification of cas no
The CAS Registry Mumber 7645-81-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,4 and 5 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7645-81:
(6*7)+(5*6)+(4*4)+(3*5)+(2*8)+(1*1)=120
120 % 10 = 0
So 7645-81-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H16O/c1-4-9(2)11-5-7-12(8-6-11)10(3)13/h5-9H,4H2,1-3H3
7645-81-0Relevant articles and documents
Nickel-catalyzed cross-coupling of alkyl zinc halides for the formation of C(sp2)-C(sp3) bonds: Scope and mechanism
Phapale, Vilas B.,Guisan-Ceinos, Manuel,Bunuel, Elena,Cardenas, Diego J.
supporting information; experimental part, p. 12681 - 12688 (2010/06/12)
Optimal conditions for a general Ni-catalysed Negishi cross-coupling of alkyl zinc halides with aryl, heteroaryl and alkenyl halides have been determined. These conditions allow the reaction to take place smoothly, with low catalyst loading, and in the pr
