76-23-3

Basic information

• Product Name: tetrabarbital
• Synonyms: tetrabarbital;Tetrabartital;5-ethyl-5-(1-ethylbutyl)barbituric acid;5-ethyl-5-hexan-3-yl-1,3-diazinane-2,4,6-trione
• CAS NO: 76-23-3
• Molecular Formula: C₁₂H₂₀N₂O₃
• Molecular Weight: 240.301
• EINECS: 200-946-6
• Mol File: 76-23-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 122°
• Appearance: /
• Density: 1.064g/cm³
• Refractive Index: 1.466
• PKA: 7.93±0.10(Predicted)
• CAS DataBase Reference: tetrabarbital(CAS DataBase Reference)
• NIST Chemistry Reference: tetrabarbital(76-23-3)
• EPA Substance Registry System: tetrabarbital(76-23-3)

Safety Data

• Hazardous Substances Data: 76-23-3(Hazardous Substances Data)

Usage

Description

Tetrabarbital, also known as pentobarbital or pentobarbitone, is a sedative-hypnotic medication belonging to the class of barbiturate drugs. It is characterized by its ability to depress the central nervous system, leading to a calming and sedative effect. Tetrabarbital enhances the activity of the neurotransmitter gamma-aminobutyric acid (GABA), which results in the inhibition of brain activity and promotes sleepiness. Due to its potential for addiction, abuse, and overdose, it is prescribed for short-term use under strict medical supervision to avoid tolerance, dependence, and withdrawal symptoms.

Uses

Used in Pharmaceutical Industry:
Tetrabarbital is used as a sedative-hypnotic medication for the treatment of insomnia, epileptic seizures, and as an anesthetic for surgical procedures. Its application is based on its ability to depress the central nervous system, enhancing the activity of GABA and promoting sleepiness.
Used in Medical Treatments:
Tetrabarbital is used as a short-term treatment for insomnia due to its sedative effects, helping patients achieve restful sleep. It is also used in the management of epileptic seizures, where its calming effect on the central nervous system helps control seizure activity.
Used in Surgical Procedures:
In the field of anesthesiology, tetrabarbital is used as an anesthetic agent to induce a state of unconsciousness during surgical procedures. Its sedative and calming effects on the central nervous system make it suitable for this application.

InChI:InChI=1/C12H20N2O3/c1-4-7-8(5-2)12(6-3)9(15)13-11(17)14-10(12)16/h8H,4-7H2,1-3H3,(H2,13,14,15,16,17)