756526-01-9 Usage
Description
FMoc-NH-PEG12-CH2CH2COOH, also known as Fmoc-NH-PEG12-propionic acid, is a modified form of propionic acid that incorporates Fmoc (9-FLUORENYLME-THOXYCARBONYL) and PEG12 (polyethylene glycol 12) groups. FMoc-NH-PEG12-CH2CH2COOH is characterized by its viscous, colorless to yellow liquid appearance and is particularly useful in the synthesis of peptides and biomolecules. It can be employed to tether peptides to proteins or other large biomolecules, such as nucleic acids, with the attachment of the hydrophobic peptide, NH2-PEG12, effectively reducing aggregation.
Uses
Used in Pharmaceutical Industry:
FMoc-NH-PEG12-CH2CH2COOH is used as a synthetic building block for the development of novel pharmaceutical compounds. Its ability to tether peptides to proteins and other biomolecules makes it a valuable tool in the creation of targeted drug delivery systems and the enhancement of drug efficacy.
Used in Biotechnology Industry:
In the biotechnology sector, FMoc-NH-PEG12-CH2CH2COOH is utilized as a key component in the synthesis of bioconjugates and biocompatible materials. FMoc-NH-PEG12-CH2CH2COOH's capacity to reduce aggregation through the attachment of the NH2-PEG12 peptide makes it an essential ingredient in the development of stable and effective bioproducts.
Used in Research and Development:
FMoc-NH-PEG12-CH2CH2COOH is employed as a research tool in the field of molecular biology and chemistry. Its unique properties allow scientists to explore new methods of peptide and biomolecule synthesis, potentially leading to breakthroughs in drug design and the creation of advanced materials for various applications.
References
https://www.aapptec.com/fmocnhpeg12propionic-acid-i-396.html
Str?mgaard, Kristian, A. Bach, and K. B. Nissen. "FATTY ACID DERIVATIVES OF DIMERIC INHIBITORS OF PSD-95.", WO/2015/078477. 2015.
Masayasu Kuwahara, et al. "Synthesis of oxy-peptide nucleic acids with mixed sequences." Nucleic acids symposium series 42.42(1999):31.
Check Digit Verification of cas no
The CAS Registry Mumber 756526-01-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,6,5,2 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 756526-01:
(8*7)+(7*5)+(6*6)+(5*5)+(4*2)+(3*6)+(2*0)+(1*1)=179
179 % 10 = 9
So 756526-01-9 is a valid CAS Registry Number.
