7471-13-8

Basic information

• Product Name: 4-methyl-N-[(E)-pyridin-2-ylmethylidene]aniline
• CAS NO: 7471-13-8
• Molecular Formula: C₁₃H₁₂N₂
• Molecular Weight: 196.2478
• Mol File: 7471-13-8.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 351.9°C at 760 mmHg
• Flash Point: 166.6°C
• Density: 1.01g/cm³
• Vapor Pressure: 8.09E-05mmHg at 25°C
• Refractive Index: 1.568
• CAS DataBase Reference: 4-methyl-N-[(E)-pyridin-2-ylmethylidene]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-[(E)-pyridin-2-ylmethylidene]aniline(7471-13-8)
• EPA Substance Registry System: 4-methyl-N-[(E)-pyridin-2-ylmethylidene]aniline(7471-13-8)

Safety Data

• Hazardous Substances Data: 7471-13-8(Hazardous Substances Data)

Usage

General Description

4-methyl-N-[(E)-pyridin-2-ylmethylidene]aniline is a chemical compound with the molecular formula C15H15N. It is a yellow to light brownish powder and is used in organic synthesis. It is commonly used as an intermediate in the production of various pharmaceuticals, dyes, and pigments. 4-methyl-N-[(E)-pyridin-2-ylmethylidene]aniline is also known for its potential biological activity and has been investigated for its use in medicinal chemistry. Additionally, it is used as a research chemical and in the development of new materials. Due to its properties and potential applications, 4-methyl-N-[(E)-pyridin-2-ylmethylidene]aniline is of interest to those working in the fields of organic chemistry, pharmaceuticals, and material science.

Upstream product

• 1121-60-4 pyridine-2-carbaldehyde 
• 106-49-0 p-toluidine 
• 99-99-0 1-methyl-4-nitrobenzene 
• 6959-47-3 2-chloromethylpyridine hydrochloride 
• 4334-26-3 4-methyl-N-((pyridine-2-yl)methyl)benzeneamine 
• 373647-96-2 [(4-trifluoromethylphenyl)imino methyl]pyridine 
• 26930-67-6 N-(pyrid-2-ylmethylene)-p-methoxyphenylamine 
• 29202-08-2 4‐bromo‐N‐((pyridin‐2‐yl)methylene)benzenamine 
• 1112-67-0 tetrabutyl-ammonium chloride 
• 54010-75-2 zinc trifluoromethanesulfonate 
• 1539-42-0 bis[(2-pyridyl)methyl]amine 

Downstream Products

• 415678-23-8 4-N-p-methylphenylamino-4-[α-pyridyl]-1-butene 
• 186594-16-1 mer-trichlorooxo(N-p-tolyl-2-pyridinecarboxaldimine)rhenium(V) 
• 152978-57-9 mer-trichloro(triphenylphosphine oxide)(N-p-tolyl-2-pyridinecarboxaldimine)rhenium(III) 
• 181063-26-3 bis(N-p-tolyl-pyridine-aldimine)copper(I) perchlorate 
• 882994-54-9 [Ru(η5-C5H5)(NC5H4CHNC6H4-4-Me)(CH3CN)]PF6 
• 921622-60-8 [Cu((4-methylphenyl)pyridin-2-ylmethylene-amine)(PPh₃)2]ClO₄ 
• 882994-56-1 [Ru(η5-C5H5)(NC5H4CHNC6H4-4-Me)(CO)]PF6 
• 110-89-4 piperidine 
• 26930-67-6 N-(pyrid-2-ylmethylene)-p-methoxyphenylamine 
• 43145-07-9 (3-(trifluoromethyl)phenyl)pyridine-2-ylmethylene-amine 
• 29202-08-2 4‐bromo‐N‐((pyridin‐2‐yl)methylene)benzenamine 
• 35558-36-2 dipiperidinomethyl-2 pyridine 

Relevant articles and documents

N,N-Chelate nickel(II) complexes bearing Schiff base ligands as efficient hydrogenation catalysts for amine synthesis

Five N, N-chelate nickel (II) complexes bearing N-(2-pyridinylmethylene)-benzylamine ligands with different substituent groups were synthesized in good yields. The nickel complexes exhibited prominent catalytic efficiency toward amine synthesis from nitro compounds by using NaBH4 or H2 as hydrogen source through two catalytic systems. Various amines with different substituents were obtained in moderate to excellent yields. All substrates with electron-donating and electron-withdrawing properties were tolerated in the two reduction systems. Given the efficient catalytic activity, broad substance scope, and mild reduction conditions, the nickel catalysts have potential applications in industrial production.

Diastereoselective Control of Tetraphenylethene Reactivity by Metal Template Self-Assembly

The reaction of 4,4′,4′′,4′′′-(ethene-1,1,2,2-tetrayl)tetraaniline with 2-pyridinecarboxaldehyde and iron(II) chloride resulted, after aqueous workup, in the diastereoselective formation of an [Fe2L3]4+ triple-stranded hel

Experimental and mechanistic insights into copper(ii)-dioxygen catalyzed oxidative: N -dealkylation of N -(2-pyridylmethyl)phenylamine and its derivatives

A di-(2-pyridylmethyl)phenylamine ((PyCH2)2NPh) supported Cu(ii)/O2 catalytic system was explored with the synthesis of pyridylmethyl-based compounds of carboxylate (PyCOOH), amide (PyC(O)NHPh), and imine (PyCHNPh) from the oxidative N-dealkylation of N-(2-pyridylmethyl)phenylamine (PyCH2NHPh) and its derivatives, by means of controlling the addition of a base and/or water to the reaction system under a dioxygen atmosphere at room temperature. Experimental studies showed that the imine and amide species could be precursors in succession in the way to the final oxidation state of carboxylates. A cyclic catalytic mechanism was proposed including the base triggered C-H bond activation of the 2-pyridylmethyl group (PyCH2-) and the intermolecular Cu-OOH α-hydrogen atom abstraction from the coordinated imine substrate (PyCHNPh).