7465-16-9

Basic information

• Product Name: 4-(diethoxymethyl)phenol
• CAS NO: 7465-16-9
• Molecular Formula: C₁₁H₁₆O₃
• Molecular Weight: 196.2429
• Mol File: 7465-16-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 266.3°C at 760 mmHg
• Flash Point: 114.8°C
• Density: 1.068g/cm³
• Vapor Pressure: 0.00531mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: 4-(diethoxymethyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(diethoxymethyl)phenol(7465-16-9)
• EPA Substance Registry System: 4-(diethoxymethyl)phenol(7465-16-9)

Safety Data

• Hazardous Substances Data: 7465-16-9(Hazardous Substances Data)

Usage

Description

4-(diethoxymethyl)phenol, with the molecular formula C11H16O3, is an aromatic phenol derivative characterized by its colorless to pale yellow liquid appearance and a pleasant odor. It is soluble in organic solvents such as ethanol and ether, and is recognized for its adhesive and bonding properties, making it a versatile intermediate in the production of pharmaceuticals and other organic compounds.

Uses

Used in Pharmaceutical Industry:
4-(diethoxymethyl)phenol is used as an intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and medicinal compounds.
Used in Adhesive and Coating Formulation:
4-(diethoxymethyl)phenol is used as a crosslinking agent in the formulation of adhesives, coatings, and sealants, enhancing their adhesive and bonding properties.
Used in Polymer and Resin Synthesis:
Due to its reactivity and versatility, 4-(diethoxymethyl)phenol is utilized in the synthesis of various polymers and resins, playing a crucial role in the development of a wide range of industrial and commercial products.

Upstream product

• 64-17-5 ethanol 
• 123-08-0 4-hydroxy-benzaldehyde 
• 122-51-0 orthoformic acid triethyl ester 

Relevant articles and documents

Preparation method of 3-bromo-4-hydroxybenzaldehyde

The invention discloses a preparation method of 3-bromo-4-hydroxybenzaldehyde. The preparation method comprises the following steps: (1) carrying out a bromination reaction on p-hydroxybenzene methylal and bromine to obtain 3-bromo-4-hydroxybenzene methylal; and (2) carrying out a hydrolysis reaction on the 3-bromo-4-hydroxybenzene methylal obtained in the step (1), and carrying out post-treatmentafter the reaction is finished to obtain the 3-bromo-4-hydroxybenzaldehyde. According to the preparation method, aldehyde is replaced with acetal for the bromination reaction, so that generation of adibromo product is effectively avoided, the yield and purity of a monobromo product are improved, and industrialization is facilitated.

Bronsted acidic ionic liquids as efficient and recyclable catalysts for protection of carbonyls to acetals and ketals under mild conditions

A series of acidic ionic liquids have been used as efficient catalysts for the protection of various carbonyl compounds at room temperature. The features of mild conditions, satisfactory isolated yield, simple workup, and the recyclability of the catalyst were present in this process. Copyright Taylor & Francis, Inc.

An efficient and versatile procedure for the synthesis of acetals from aldehydes and ketones catalyzed by lithium tetrafluoroborate

Acetals are obtained in good to excellent yields by treatment of aldehydes and ketones with trialkyl orthoformate and the corresponding alcohol in the presence of a catalytic amount of lithium tetrafluoroborate. Due to the mild reaction conditions, this method is compatible with acid-sensitive substrates.