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744254-10-2

21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride is a synthetic corticosteroid derivative characterized by its potent anti-inflammatory and immunosuppressive properties. It is a modified version of the naturally occurring hormone cortisol, with the addition of a fluorine atom at the 9th position and an amino group at the 21st position, which enhances its therapeutic efficacy. This chemical is typically administered in various forms, including tablets, injections, and creams, to treat a wide range of inflammatory and allergic conditions.

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  • 17-(2-amino-1-oxoethyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one hydrochloride

    Cas No: 744254-10-2

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  • 21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride

    Cas No: 744254-10-2

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  • 21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride

    Cas No: 744254-10-2

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  • 744254-10-2 Structure

  • Basic information

    1. Product Name: 21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride
    2. Synonyms: 21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride;21-amino-9-fluoro-11β,17a-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione,hydrochloride
    3. CAS NO:744254-10-2
    4. Molecular Formula: C22H30FNO4.HCl
    5. Molecular Weight: 427.94
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 744254-10-2.mol
    9. Article Data: 0

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 578°C at 760 mmHg
    3. Flash Point: 303.4°C
    4. Appearance: /
    5. Density: N/A
    6. Vapor Pressure: 9.1E-16mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride(CAS DataBase Reference)
    11. NIST Chemistry Reference: 21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride(744254-10-2)
    12. EPA Substance Registry System: 21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride(744254-10-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 744254-10-2(Hazardous Substances Data)

744254-10-2 Usage

Uses

Used in Pharmaceutical Industry:
21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride is used as an anti-inflammatory and immunosuppressive agent for the treatment of various conditions, such as asthma, arthritis, and skin disorders. Its application in this industry is due to its ability to reduce inflammation and suppress the immune response, providing relief from symptoms associated with these conditions.
Used in Asthma Treatment:
In the respiratory industry, 21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride is used as a controller medication for asthma. It helps to reduce airway inflammation and prevent asthma attacks by suppressing the immune response and decreasing the production of inflammatory mediators.
Used in Arthritis Treatment:
In the rheumatology industry, this corticosteroid is used as a disease-modifying antirheumatic drug (DMARD) for the treatment of various forms of arthritis, including rheumatoid arthritis and osteoarthritis. It helps to alleviate joint pain, swelling, and stiffness by reducing inflammation and modulating the immune system.
Used in Dermatology:
21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride is used as a topical treatment for various skin disorders in the dermatology industry. It is effective in managing conditions such as eczema, psoriasis, and dermatitis by reducing skin inflammation, itching, and redness.
It is crucial to use this corticosteroid under the guidance of a healthcare professional, as it may cause side effects and interact with other medications. Proper dosage and administration are essential to ensure its safety and effectiveness in treating the intended conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 744254-10-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,4,2,5 and 4 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 744254-10:
(8*7)+(7*4)+(6*4)+(5*2)+(4*5)+(3*4)+(2*1)+(1*0)=152
152 % 10 = 2
So 744254-10-2 is a valid CAS Registry Number.
InChI:InChI=1/C22H30FNO4.ClH/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24;/h6-7,9,12,15-17,26,28H,4-5,8,10-11,24H2,1-3H3;1H/t12?,15-,16-,17?,19-,20-,21?,22-;/m0./s1

744254-10-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 21-Amino-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione hydrochloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:744254-10-2 SDS

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