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  • 7376-66-1 Structure
  • Basic information

    1. Product Name: deterenol
    2. Synonyms: deterenol;4-Hydroxy-α-[(isopropylamino)methyl]benzyl alcohol;Paraproterenol;p-Hydroxy-α-[(isopropylamino)methyl]benzyl alcohol;PI-39;WIN-833;DL-N-Isopropyloctopamine
    3. CAS NO:7376-66-1
    4. Molecular Formula: C11H17NO2
    5. Molecular Weight: 195.25818
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 7376-66-1.mol
    9. Article Data: 1
  • Chemical Properties

    1. Melting Point: 138-140℃
    2. Boiling Point: 331.93°C (rough estimate)
    3. Flash Point: 143oC
    4. Appearance: /
    5. Density: 1.0654 (rough estimate)
    6. Vapor Pressure: 1.11E-05mmHg at 25°C
    7. Refractive Index: 1.5330 (estimate)
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 9.97±0.26(Predicted)
    11. CAS DataBase Reference: deterenol(CAS DataBase Reference)
    12. NIST Chemistry Reference: deterenol(7376-66-1)
    13. EPA Substance Registry System: deterenol(7376-66-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 7376-66-1(Hazardous Substances Data)

7376-66-1 Usage

Description

Deterenol, also known as isopropylnoradrenaline, is a synthetic chemical compound that functions as a selective β1-adrenergic receptor agonist. It is recognized for its role as a bronchodilator and in the management of specific heart conditions, such as heart failure and cardiogenic shock. Deterenol operates by activating the β1-adrenergic receptors in the heart, which results in enhanced force and rate of contractions, as well as improved cardiac output. Additionally, it facilitates the relaxation of smooth muscles in the bronchioles, promoting easier breathing. Despite its potential therapeutic advantages, the use of deterenol should be approached with caution and under the guidance of a healthcare professional to mitigate the risk of side effects and medication interactions.

Uses

Used in Pharmaceutical Industry:
Deterenol is used as a bronchodilator for the treatment of respiratory conditions characterized by constricted airways, such as asthma and chronic obstructive pulmonary disease (COPD). Its ability to relax the smooth muscles in the bronchioles aids in improving lung function and easing breathing difficulties.
Used in Cardiology:
Deterenol is utilized as a therapeutic agent in the management of heart conditions like heart failure and cardiogenic shock. By stimulating the β1-adrenergic receptors in the heart, it increases the force and rate of cardiac contractions, leading to an enhancement in cardiac output. This helps in improving the overall heart function and addressing the symptoms associated with these conditions.
Used in Drug Formulation:
Deterenol is incorporated into various pharmaceutical formulations, such as tablets, injections, and inhalers, to ensure targeted delivery and optimal therapeutic effects. These formulations are designed to provide controlled release and appropriate dosages, ensuring the safe and effective use of deterenol in treating the intended medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 7376-66-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,3,7 and 6 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 7376-66:
(6*7)+(5*3)+(4*7)+(3*6)+(2*6)+(1*6)=121
121 % 10 = 1
So 7376-66-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H17NO2/c1-8(2)12-7-11(14)9-3-5-10(13)6-4-9/h3-6,8,11-14H,7H2,1-2H3

7376-66-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[1-Hydroxy-2-(isopropylamino)ethyl]phenol

1.2 Other means of identification

Product number -
Other names para-phenylethynylphenyl isocyanate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7376-66-1 SDS

7376-66-1Downstream Products

7376-66-1Relevant articles and documents

β-Adrenoceptor stimulant properties of amidoalkylamino-substituted 1-aryl-2-ethanols and 1-(aryloxy)-2-propanols

Barlow,Main,Snow

, p. 315 - 322 (2007/10/02)

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