726185-65-5

Basic information

• Product Name: tert-butyl 4-[4-(ethoxycarbonyl)benzylidene]piperidine-1-carboxylate
• Synonyms: tert-butyl 4-[4-(ethoxycarbonyl)benzylidene]piperidine-1-carboxylate
• CAS NO: 726185-65-5
• Molecular Weight: 345.439
• Mol File: 726185-65-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-[4-(ethoxycarbonyl)benzylidene]piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-[4-(ethoxycarbonyl)benzylidene]piperidine-1-carboxylate(726185-65-5)
• EPA Substance Registry System: tert-butyl 4-[4-(ethoxycarbonyl)benzylidene]piperidine-1-carboxylate(726185-65-5)

Safety Data

• Hazardous Substances Data: 726185-65-5(Hazardous Substances Data)

Upstream product

• 14295-52-4 4-(diethyoxyphosphorylmethyl)benzoic acid methyl ester 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 85838-94-4 N-Boc-1,2,3,6-tetrahydropyridine 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 159635-49-1 tert-butyl 4-methylidenepiperidine-1-carboxylate 

Downstream Products

• 726185-64-4 tert-butyl 4-[(4-ethoxycarbonylphenyl)methyl]piperidine-1-carboxylate 
• 1425970-99-5 tert-butyl 4-{4-[(3-methyl-2-oxoimidazolidin-1-yl)methyl]benzylidene}piperidine-1-carboxylate 
• 1425971-11-4 tert-butyl 4-[4-({[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]oxy}methyl)benzylidene]piperidine-1-carboxylate 
• 1425971-17-0 tert-butyl 4-[4-(piperidin-1-ylmethyl)benzylidene]piperidine-1-carboxylate 
• 1425972-67-3 tert-butyl 4-bromo-4-{bromo[4-(ethoxycarbonyl)phenyl]methyl}piperidine-1-carboxylate 
• 1425972-68-4 tert-butyl 4-{bromo[4-(ethoxycarbonyl)phenyl]methylidene}piperidine-1-carboxylate 
• 1425970-96-2 tert-butyl 4-(4-{[(4R)-4-{[tert-butyl(dimethyl)silyl]oxy}-2-oxopyrrolidine-1-yl]methyl}benzylidene)piperidine-1-carboxylate 
• 1425970-78-0 tert-butyl 4-{4-[(3-methoxy-2-oxopyridin-1(2H)-yl)methyl]benzylidene}piperidine-1-carboxylate 
• 1425970-72-4 tert-butyl 4-{4-[(2-oxopyridin-1(2H)-yl)methyl]benzylidene}piperidine-1-carboxylate 
• 1425970-71-3 tert-butyl 4-(4-(bromomethyl)benzylidene)piperidine-1-carboxylate 
• 1425970-70-2 tert-butyl 4-(4-(hydroxymethyl)benzylidene)piperidine-1-carboxylate 

Relevant articles and documents

TRICYCLIC DEGRADERS OF IKAROS AND AIOLOS

Tricyclic cereblon binders for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway for therapeutic applications are described.

Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent anti-HIV-1 activity

We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their metabolic stability in human hepatic microsomes. Introducing a carbamoyl group into the phenyl ring of the 4-benzylpiperidine moiety