7244-82-8Relevant articles and documents
Soft-enolization Baker-Venkataraman Rearrangement Enabled Total Synthesis of Dirchromones and Related 2-Substituted Chromones
St-Gelais, Alexis,Alsarraf, Jér?me,Legault, Jean,Gauthier, Charles,Pichette, André
supporting information, p. 7424 - 7428 (2019/01/03)
A seven-step total synthesis of the original scaffold of cytotoxic dirchromones involving an unprecedented soft-enolization Baker-Venkataraman rearrangement was designed. The methodology enabled access to naturally occurring dirchromone 1 (21% overall yield) at gram-scale, which was screened for cytotoxicity against 13 cancer cell lines. The scope of the soft-enolization Baker-Venkataraman rearrangement encompasses diversely substituted dirchromones, including flavonoids, 2-styrylchromones, and 2-phenylethylchromones.
8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(thio-, sulfinyl- and sulfonyl-containing acyl)hydrazides
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, (2008/06/13)
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S,S-Dialkyl Dithiocarbonates as a Convenient Source of Alkanethiols: an Improved Synthesis of Alkylthiocarboxylic Acids
Cadamuro, Silvano,Degani, Iacopo,Fochi, Rita,Regondi, Valeria
, p. 1070 - 1074 (2007/10/02)
A wide variety of β-alkylthiocarboxylic acids are obtained by addition of alkanethiols - generated in situ from S,S-dialkyl dithiocarbonates - to appropriate α,β-unsaturated carboxylic acids in good to excellent yields.