7209-00-9 Usage
Description
2-Bromoglutaric acid diethylester, with the molecular formula C9H15BrO4, is a diethyl ester of 2-bromoglutaric acid, a derivative of glutaric acid. This colorless to pale yellow liquid exhibits a fruity odor and is soluble in water, ethanol, and ether. It is recognized for its role as an intermediate in the production of pharmaceuticals and fine chemicals, as well as its utility in organic synthesis for preparing various compounds.
Uses
Used in Pharmaceutical Industry:
2-Bromoglutaric acid diethylester is used as an intermediate for the synthesis of pharmaceuticals, contributing to the development of new drugs and improving the efficacy of existing ones.
Used in Fine Chemicals Production:
In the fine chemicals industry, 2-Bromoglutaric acid diethylester serves as a key intermediate, facilitating the production of specialty chemicals with specific applications in various fields.
Used in Organic Synthesis:
2-Bromoglutaric acid diethylester is utilized as a reagent in organic synthesis, enabling the preparation of a wide range of compounds for research and industrial applications.
Safety Precautions:
It is crucial to handle 2-Bromoglutaric acid diethylester with care due to its potential harmful effects if ingested, inhaled, or absorbed through the skin. Adequate safety measures, including the use of personal protective equipment and proper disposal methods, should be implemented when working with this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 7209-00-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,0 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7209-00:
(6*7)+(5*2)+(4*0)+(3*9)+(2*0)+(1*0)=79
79 % 10 = 9
So 7209-00-9 is a valid CAS Registry Number.
7209-00-9Relevant articles and documents
Schwenk,Papa
, p. 3627 (1948)
GADOLINIUM BEARING PCTA-BASED CONTRAST AGENTS
-
, (2020/03/02)
The present invention relates to the RRR/SSS pair of enantiomers of the of Gd(PCTA-tris-glutamic acid), the single enantiomers of the pair, the pharmaceutically acceptable salts thereof, their amide derivatives, and compositions comprising at least 50% of these compounds.
Synthesis of 2-(Quinoxalin-2-ylamino-benzotriazolyl) Pentanedioic Derivatives as Potential Anti-Folate Agents
Briguglio,Piras,Corona,Pirisi,Burrai,Boatto,Gavini,Rassu
, p. 1721 - 1737 (2016/11/23)
Anti-folate agents had a significant impact on therapeutic treatment plans for diseases such as cancer, and bacterial and parasitic infections, notably malaria. Quinoxaline derivatives showed in vitro anticancer activity and were able to inhibit both the dihydrofolate reductase and thymidylate synthase. Here, we decided to combine the chemical properties of quinoxalines and quinoxaline 1,4-dioxides with those of benzotriazole nucleus with the aim to evaluate the resulting biological properties. Two main new series, including more than 60 compounds, were prepared. In the first one, the benzotriazole moiety was linked through the nitrogen atoms 1, 2, or 3, to a glutaric acid substituent to simulate a glutamic moiety. In the second series, the glutaric acid was substituted with acetic acid moiety to evaluate the effects of steric hindrance. Here, we describe the multistep chemical processes to obtain all titled quinoxalines starting from commercially available diamines. The classical oxidation of selected quinoxalines was unsuccessful, and we have come to an independent synthetic pathway to obtain new derivatives linked to the benzotriazole moieties starting from synthons bearing N-oxide functionality.
