71888-57-8

Basic information

• Product Name: pyrrolidine-1-valeronitrile
• Synonyms: pyrrolidine-1-valeronitrile;1-Pyrrolidinepentanenitrile;5-Pyrrolizinovaleronitrile
• CAS NO: 71888-57-8
• Molecular Formula: C₉H₁₆N₂
• Molecular Weight: 152.23674
• EINECS: 276-146-6
• Mol File: 71888-57-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 269.3°C at 760 mmHg
• Flash Point: 109.9°C
• Appearance: /
• Density: 0.949g/cm³
• Vapor Pressure: 0.00732mmHg at 25°C
• Refractive Index: 1.475
• CAS DataBase Reference: pyrrolidine-1-valeronitrile(CAS DataBase Reference)
• NIST Chemistry Reference: pyrrolidine-1-valeronitrile(71888-57-8)
• EPA Substance Registry System: pyrrolidine-1-valeronitrile(71888-57-8)

Safety Data

• Hazardous Substances Data: 71888-57-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H16N2/c10-6-2-1-3-7-11-8-4-5-9-11/h1-5,7-9H2

Upstream product

• 123-75-1 pyrrolidine 
• 5414-21-1 5-bromopentan-1-nitrile 

Downstream Products

• 71302-71-1 5-(pyrrolidin-1-yl)pentan-1-amine 

Relevant articles and documents

Heteroatom-directed alkylcyanation of alkynes

Alkanenitriles having a heteroatom such as nitrogen, oxygen, and sulfur at the γ-position are found to add across alkynes stereo-and regioselectively by nickel/Lewis acid catalysis to give highly substituted acrylonitriles. The heteroatom functionalities likely coordinate to the nickel center to make oxidative addition of the C-CN bonds of the alkyl cyanides kinetically favorable, forming a five-membered nickelacycle intermediate and, thus, preventing β-hydride elimination to allow the alkylcyanation reaction.