7157-15-5

Basic information

• Product Name: 2-BROMOMANDELIC ACID
• Synonyms: 2-BROMOMANDELIC ACID;(R)-2-Bromomandelic;(2R)-Hydroxy(2-bromophenyl)aceticacid;(R)-2-BROMOMANDELIC ACID;2-(2-BroMophenyl)-2-hydroxyacetic acid
• CAS NO: 7157-15-5
• Molecular Formula: C₈H₇BrO₃
• Molecular Weight: 231.04
• Mol File: 7157-15-5.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 384°C at 760 mmHg
• Flash Point: 186°C
• Appearance: /
• Density: 1.759g/cm³
• Vapor Pressure: 1.39E-06mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-BROMOMANDELIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMOMANDELIC ACID(7157-15-5)
• EPA Substance Registry System: 2-BROMOMANDELIC ACID(7157-15-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 7157-15-5(Hazardous Substances Data)

Usage

General Description

2-Bromomandelic Acid is a chemical compound often characterized as a derivatized phenolic acid. It is also known by other names such as α-Bromo-2,3-dihydroxybenzeneacetic acid or 2-Bromophenylglycolic acid. This organic molecule contains bromine, one of the halogens, and a carboxylic acid group, which confers it certain potential reactivity. Like other phenolic acids, its structure comprises a phenolic ring, implying that it may exhibit aromatic properties. Its use is generally seen in scientific research, particularly synthetic chemistry, where it can act as a precursor or intermediary to other compounds. Being a niche chemical, its production and handling are typically subject to specific regulations.

InChI:InChI=1/C8H7BrO3/c9-6-4-2-1-3-5(6)7(10)8(11)12/h1-4,7,10H,(H,11,12)

Upstream product

• 2142-69-0 2-bromophenyl methyl ketone 
• 70-11-1 α-bromoacetophenone 
• 6630-33-7 ortho-bromobenzaldehyde 
• 18698-97-0 ortho-bromophenylacetic acid 
• 52923-21-4 2-(2-bromophenyl)-2-hydroxyacetonitrile 
• 75-25-2 Bromoform 

Downstream Products

• 32345-77-0 (R)-(-)-2-bromo-mandelic acid 
• 1236046-50-6 (2-bromophenyl)(2-(pyridin-2-yl)phenyl)methanone 
• 6630-33-7 ortho-bromobenzaldehyde 
• 1402890-79-2 methyl 2-(tert-butoxy)-2-[2-(3,4-dihydro-2H-1-benzopyran-6-yl)phenyl]acetate 
• 1402890-78-1 methyl 2-(2-bromophenyl)-2-(tert-butoxy)acetate 
• 1402890-71-4 2-(tert-butoxy)-2-[2-(3,4-dihydro-2H-1-benzopyran-6-yl)phenyl]acetic acid 
• 21165-13-9 methyl 2-(2-bromophenyl)-2-hydroxyacetate 
• 181040-14-2 methyl (RS)-(2-bromophenyl)-[2-cyano-5-(thien-3-ylmethoxy)phenoxy]acetate 
• 43063-97-4 methyl 2-bromo-2-(2-bromophenyl) acetate 
• 30297-34-8 5-(2-bromo-phenyl)-2-dimethylamino-oxazol-4-one 

Relevant articles and documents

Nitrilases

The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition, methods of designing new nitrilases and methods of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.

Solid phase behavior in the chiral systems of various 2-hydroxy-2-phenylacetic acid (mandelic acid) derivatives

The solid phase behavior of a series of monosubstituted F-, Cl-, Br-, I-, and CH3- and two 2,4-halogen-disubstituted 2-hydroxy-2-phenylacetic acid (mandelic acid) derivatives was investigated. The study includes detailed information about melting temperature, melting enthalpy, X-ray diffraction data, as well as selected binary phase diagrams of the respective chiral systems. Aside from the known metastable conglomerate 2-chloromandelic acid, evidence for two more metastable conglomerates was found.

Amberlyst A-26: An efficient and reusable heterogeneous catalyst for a one-pot oxidation-Cannizarro reaction

Amberlyst A-26 catalyses the efficient synthesis of α-hydroxy- arylacetic acids from aryl methyl ketones in the presence of SeO2. After simple separation, the catalyst does not lose its activity and can be reused without significant loss in activity for at least four cycles.