7153-23-3

Basic information

• Product Name: 6,7-DIMETHYLQUINOXALINE
• Synonyms: 6,7-DIMETHYLQUINOXALINE;SALOR-INT L168912-1EA;Inchi=1/C10H10N2/C1-7-5-9-10(6-8(7)2)12-4-3-11-9/H3-6H,1-2h;Quinoxaline, 6,7-dimethyl-
• CAS NO: 7153-23-3
• Molecular Formula: C₁₀H₁₀N₂
• Molecular Weight: 158.2
• Mol File: 7153-23-3.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 281.7 °C at 760 mmHg
• Flash Point: 119.3 °C
• Appearance: /
• Density: 1.109 g/cm³
• Vapor Pressure: 0.00598mmHg at 25°C
• Refractive Index: 1.617
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6,7-DIMETHYLQUINOXALINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-DIMETHYLQUINOXALINE(7153-23-3)
• EPA Substance Registry System: 6,7-DIMETHYLQUINOXALINE(7153-23-3)

Safety Data

• Hazardous Substances Data: 7153-23-3(Hazardous Substances Data)

Usage

General Description

6,7-Dimethylquinoxaline is a chemical compound with the molecular formula C10H8N2. It is a bicyclic heteroarene with a quinoxaline core, and it is a colorless solid. 6,7-DIMETHYLQUINOXALINE has various uses in organic synthesis, such as in the preparation of pharmaceuticals, dyes, and agrochemicals. It is also used as a building block in the production of other complex organic compounds. Additionally, 6,7-Dimethylquinoxaline has been studied for its potential biological activities, including its antimicrobial and anticancer properties. Overall, this compound has important applications in both the chemical and pharmaceutical industries.

InChI:InChI=1/C10H10N2/c1-7-5-9-10(6-8(7)2)12-4-3-11-9/h3-6H,1-2H3

Upstream product

• 6972-71-0 4,5-dimethyl-2-nitrobenzenamine 
• 107-21-1 ethylene glycol 
• 141-43-5 ethanolamine 
• 3171-45-7 4,5-dimethyl-1,2-phenylenediamine 
• 517-21-5 glyoxal sodium bisulfite 
• 131543-46-9 Glyoxal 

Downstream Products

• 77093-89-1 6,7-dimethylquinoxaline 1-oxide 
• 282528-23-8 6,7-dihydrocyclobuta[g]quinoxaline 
• 10579-68-7 6,7-dimethyl-1,2,3,4-tetrahydroquinoxaline 
• 66102-32-7 1,4,6,7-tetramethyl-1,2,3,4-tetrahydroquinoxaline 
• 226698-28-8 2-Fluoro-6,7-dimethylquinoxaline 

Relevant articles and documents

Synthesis of a novel constrained α-amino acid with quinoxaline side chain : 7-Amino-6,7-dihydro-8H-cyclopenta[g]quinoxaline-7-carbox-ylic acid

A novel constrained 7-amino-6,7-dihydro-8H-cyclopenta[g]quinoxaline-7- carboxylic acid derivative was prepared starting from 4,5-dimethyl-o-phenylenediamine.

Tetrabutylammonium Bromide-Catalyzed Transfer Hydrogenation of Quinoxaline with HBpin as a Hydrogen Source

A metal-free environmentally benign, simple, and efficient transfer hydrogenation process of quinoxaline has been developed using the HBpin reagent as a hydrogen source. This reaction is compatible with a variety of quinoxalines offering the desired tetrahydroquinoxalines in moderate-to-excellent yields with Bu4NBr as a noncorrosive and low-cost catalyst.

Iron-catalyzed Minisci acylation of N-heteroarenes with α-keto acids

An efficient and mild protocol has been developed for the Minisci acylation reactions of nitrogen-containing heteroarenes with α-keto acids. Distinct from the conventional Minisci acylation conditions, the chemistry was performed using non-noble metal Fe(II), instead of expensive Ag(I) salt, as catalyst. A wide range of substrates, including aliphatic or aromatic α-keto acids, as well as various N-heteroarenes, proved to be compatible with the protocol. Scale-up experiment also demonstrates the practicality of the approach.

Efficient synthesis of quinoxalines from 2-nitroanilines and vicinal diols via a rutheniumcatalyzed hydrogen transfer strategy

Via a ruthenium-catalyzed hydrogen transfer strategy, we have demonstrated a one-pot method for efficient synthesis of quinoxalines from 2-nitroanilines and biomass-derived vicinal diols for the first time. In such a synthetic protocol, the diols and the nitro group serve as the hydrogen suppliers and acceptors, respectively. Hence, there is no need for the use of external reducing agents. Moreover, it has the advantages of operational simplicity, broad substrate scope and the use of renewable reactants, offering an important basis for accessing various quinoxaline derivatives.