7143-42-2Relevant articles and documents
Insight into the offbeat electrochemical methoxylation of isatin
Cravotto, Giancarlo,Giovenzanab, Giovanni B.,Palmisano, Giovanni,Vodopivec, Bruno
, p. 8825 - 8827 (2000)
A claim by Kazimierczuk and co-workers to have synthesized the diene 1 by electrochemical vic-dimethoxylation of isatin 2 is wrong. The product is now shown by a careful analysis of spectral data and synthesis to be in reality methyl N-(methoxycarbonyl)an
An Electrochemical Route for Special Oxidative Ring-Opening of Indoles
Qin, Hong,Yang, Zhao,Zhang, Zhen,Liu, Chengkou,He, Wei,Fang, Zheng,Guo, Kai
supporting information, p. 13024 - 13028 (2021/08/09)
A novel electrochemical protocol for the oxidative cleavage of indoles has been developed, which o?ers a simple way to access synthetically useful anthranilic acid derivatives. In undivided cells, a wide variety of indoles and alcohol compounds are examined to a?ord amide ester aromatics without using extra oxidants and stoichiometric metal catalysts, which avoids the formation of undesired by-products and exhibits high atom economy. The products we described in this perspective represent a synthetic intermediate in numerous drug molecules and industrial chemical reagents and remarkably show potential application in the future.
Beyond conventional routes, an unprecedented metal-free chemoselective synthesis of anthranilate esters via a multicomponent reaction (MCR) strategy
Sarkar, Satavisha,Khan, Abu T.
supporting information, p. 12673 - 12676 (2015/08/06)
A hitherto unreported route for the synthesis of anthranilate esters is demonstrated using 2-nitrobenzaldehyde, malonitrile and an alcohol or amine via a metal and oxidant free multicomponent reaction (MCR) strategy. This process simultaneously installs an ester and urea or urethane functionality via CO and CN bond formations via concurrent oxidation of the aldehyde group and reduction of the nitro group involving an intramolecular redox process.