711-90-0

Basic information

• Product Name: α-acetoxy-2-fluoroacetophenone
• Synonyms: α-acetoxy-2-fluoroacetophenone
• CAS NO: 711-90-0
• Molecular Weight: 196.178
• Mol File: 711-90-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: α-acetoxy-2-fluoroacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: α-acetoxy-2-fluoroacetophenone(711-90-0)
• EPA Substance Registry System: α-acetoxy-2-fluoroacetophenone(711-90-0)

Safety Data

• Hazardous Substances Data: 711-90-0(Hazardous Substances Data)

Upstream product

• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 111102-82-0 4-(2-fluorophenyl)-1,1,1-trifluoro-2,4-butanedione 
• 348-52-7 1-Fluoro-2-iodobenzene 
• 13831-31-7 Acetoxyacetyl chloride 
• 127-08-2 potassium acetate 
• 766-49-4 (2-fluorophenyl)acetylene 
• 704-97-2 3-(2-fluorophenyl)prop-2-ynoic acid 

Downstream Products

• 218771-68-7 1-(2-fluorophenyl)-2-hydroxyethan-1-one 

Relevant articles and documents

Decarboxylative Oxyacyloxylation of Propiolic Acids: Construction of Alkynyl-Containing α-Acyloxy Ketones

Novel decarboxylative oxyacyloxylation of propiolic acids has been developed. This reaction provides an efficient access to alkynyl-containing α-acyloxy ketones from readily available starting materials and exhibits significant functional group tolerance. Furthermore, oxyacyloxylation of terminal alkynes and aliphatic propiolic acids was also developed. A possible reaction mechanism is proposed based on mechanistic studies.

Synthesis of α-hydroxyacetophenones

A general method for the preparation of α-hydroxyacetophenones is presented. Functionalized arylmagnesium species are transmetalated to the corresponding arylzinc intermediates, which undergo Cu(I)-catalyzed reaction with acetoxyacetyl chloride. Acidic hy