709-49-9 Usage
Description
2,4-Dinitroiodobenzene is an organic compound that consists of a benzene ring with two nitro groups at the 2nd and 4th positions and an iodine atom attached to the benzene ring. It is known for its unique chemical properties and potential applications in various fields.
Uses
Used in Biotechnology Industry:
2,4-Dinitroiodobenzene is used as a chemical inducer for the cloning and characterization of a biotic-stress-inducible glutathione transferase from Phaseolus vulgaris. This enzyme plays a crucial role in the plant's defense mechanism against various biotic stresses, such as pathogen attacks and herbivore feeding.
The use of 2,4-Dinitroiodobenzene in this application allows researchers to study the enzyme's properties, regulation, and potential applications in improving plant resistance to biotic stresses. This knowledge can contribute to the development of more resilient crop varieties and better agricultural practices.
Synthesis Reference(s)
The Journal of Organic Chemistry, 23, p. 305, 1958 DOI: 10.1021/jo01096a608
Purification Methods
Crystallise it from EtOAc. [Beilstein 5 H 270.]
Check Digit Verification of cas no
The CAS Registry Mumber 709-49-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 709-49:
(5*7)+(4*0)+(3*9)+(2*4)+(1*9)=79
79 % 10 = 9
So 709-49-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H3IN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H
709-49-9Relevant articles and documents
Kendall,Miller
, p. 119 (1967)
Late stage iodination of biologically active agents using a one-pot process from aryl amines
Sloan, Nikki L.,Luthra, Sajinder K.,McRobbie, Graeme,Pimlott, Sally L.,Sutherland, Andrew
, p. 54881 - 54891 (2017/12/12)
A simple and effective one-pot tandem procedure that generates aryl iodides from readily available aryl amines via stable diazonium salts has been developed. The operationally simple procedure and mild conditions allow late-stage iodination of a wide range of aryl compounds bearing various functional groups and substitution patterns. A novel synthetic strategy involving the preparation of nitroaryl compounds followed by a chemoselective tin(ii) dichloride reduction and the use of the one-pot diazotisation-iodination transformation was also developed. The general applicability of this approach was demonstrated with the preparation of a number of medicinally important compounds including CNS1261, a SPECT imaging agent of the N-methyl-d-aspartate (NMDA) receptor and IBOX, a compound used to detect amyloid plaques in the brain.
Application of [Hcpy]HSO4 Broensted acidic ionic liquid for the synthesis of aryl iodides from aromatic amines
Hajipour, Abdol Reza,Seddighi, Mohadeseh
experimental part, p. 292 - 296 (2011/07/31)
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