70577-95-6 Usage
Description
METHYL 4,4,4-TRIFLUOROCROTONATE, also known as 4,4,4-Trifluoro-2-butynoic Acid Methyl Ester, is a chemical compound that serves as a versatile intermediate in the synthesis of various fluorinated pharmaceutical compounds. It is characterized by its unique molecular structure, which includes a trifluoromethyl group and a methyl ester group, making it a valuable building block for the development of new drugs and pharmaceuticals.
Uses
Used in Pharmaceutical Synthesis:
METHYL 4,4,4-TRIFLUOROCROTONATE is used as a key intermediate for the synthesis of various fluorinated pharmaceutical compounds. Its unique structure allows for the development of new drugs with improved properties, such as enhanced bioavailability, increased stability, and better targeting of specific biological pathways.
Used in the Synthesis of Perfluromethylcoumarins:
METHYL 4,4,4-TRIFLUOROCROTONATE is used as a starting material for the synthesis of Perfluromethylcoumarins, a class of compounds with potential applications in the pharmaceutical industry. These compounds may exhibit interesting biological activities and could be further developed into new therapeutic agents.
Used in the Preparation of Regioisomeric (Trifluoromethyl)-isoxazolecarboxylate Esters:
METHYL 4,4,4-TRIFLUOROCROTONATE is used as a precursor for the preparation of regioisomeric (trifluoromethyl)-isoxazolecarboxylate esters. These esters are valuable building blocks for the synthesis of complex molecules and may have potential applications in the development of new drugs and pharmaceuticals.
Used in the Synthesis of Oxime Addition Products:
METHYL 4,4,4-TRIFLUOROCROTONATE is also used in the synthesis of oxime addition products, which are important intermediates in the preparation of various organic compounds. These products may have potential applications in the pharmaceutical, agrochemical, and materials science industries, contributing to the development of new products and technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 70577-95-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,5,7 and 7 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 70577-95:
(7*7)+(6*0)+(5*5)+(4*7)+(3*7)+(2*9)+(1*5)=146
146 % 10 = 6
So 70577-95-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H5F3O2/c1-10-4(9)2-3-5(6,7)8/h2-3H,1H3/b3-2+
70577-95-6Relevant articles and documents
DABCO-catalyzed synthesis of trifluoromethylated furans from propargyl alcohols and methyl 2-perfluoroalkynoate
Chong, Qinglei,Xin, Xiaoyi,Wang, Chunxiang,Wu, Fan,Wang, Haolong,Shi, Ji-Cheng,Wan, Boshun
, p. 2105 - 2110 (2014/04/03)
The DABCO-catalyzed reaction of propargyl alcohols with methyl 2-perfluoroalkynoate to give trifluoromethylated furans in up to 98% yield under mild conditions has been developed. The established allene-enol and control experiments indicate that the react
