6918-15-6

Basic information

• Product Name: dipyridin-4-ylmethanone(SALTDATA: FREE)
• Synonyms: dipyridin-4-ylmethanone(SALTDATA: FREE);dipyridin-4-ylmethanone;Di(4-pyridinyl)methanone;Dipyridin-4-ylmethanone >=95%
• CAS NO: 6918-15-6
• Molecular Formula: C₁₁H₈N₂O
• Molecular Weight: 184.2
• Mol File: 6918-15-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 142°C
• Boiling Point: 346.381°C at 760 mmHg
• Flash Point: 167.39°C
• Appearance: /
• Density: 1.196g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.594
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.17±0.10(Predicted)
• CAS DataBase Reference: dipyridin-4-ylmethanone(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: dipyridin-4-ylmethanone(SALTDATA: FREE)(6918-15-6)
• EPA Substance Registry System: dipyridin-4-ylmethanone(SALTDATA: FREE)(6918-15-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 6918-15-6(Hazardous Substances Data)

Usage

Uses

Dipyridin-4-ylmethanone may be used as a precursor to synthesize photoresponsive ligands such as diazodi(4-pyridyl)methane, which can be used in metal-carbene hetero-spin systems. This same product was previously listed as CBR00084.

InChI:InChI=1/C11H8N2O/c14-11(9-1-5-12-6-2-9)10-3-7-13-8-4-10/h1-8H

Upstream product

• 54750-97-9 4-lithiopyridine 
• 100-48-1 pyridine-4-carbonitrile 
• 1570-45-2 isonicotinic acid ethylester 
• 1120-87-2 4-bromopyridin 
• 2459-09-8 4-pyridinecarboxylic acid, methyl ester 

Downstream Products

• 60776-05-8 γ,γ'-dipyridylmethane 
• 1600563-71-0 (2,4-dichloro-3-phenylquinolin-6-yl)(dipyridin-4-yl)methanol trifluoroacetate 
• 212246-51-0 3-[4-(4-Ethynyl-phenylethynyl)-phenyl]-1,1-di-pyridin-4-yl-prop-2-yn-1-ol 
• 212246-50-9 1,1-di-4-pyridyl-3-(4-ethynylphenyl)prop-2-yn-1-ol 
• 879081-89-7 2,6-di-tert-butyl-4-(hydroxy-di-pyridin-4-yl-methyl)-phenol 
• 879081-81-9 2,6-di-tert-butyl-4-(di-pyridin-4-yl-methylene)-cyclohexa-2,5-dienone 

Relevant articles and documents

Preparation of sterically congested Di(4-pyridyl)diazomethanes and characterization of triplet carbenes from them

(Chemical Equation Presented) Di(4-pyridyl)diazomethanes having two and four ortho chlorine groups were prepared, and the triplet carbenes generated from them were characterized by ESR and UV/vis at low temperature and time-resolved UV/vis at room tempera

Catalytic Enantioselective Pyridine N-Oxidation

The catalytic, enantioselective N-oxidation of substituted pyridines is described. The approach is predicated on a biomolecule-inspired catalytic cycle wherein high levels of asymmetric induction are provided by aspartic-acid-containing peptides as the aspartyl side chain shuttles between free acid and peracid forms. Desymmetrizations of bis(pyridine) substrates bearing a remote pro-stereogenic center substituted with a group capable of hydrogen bonding to the catalyst are demonstrated. Our approach presents a new entry into chiral pyridine frameworks in a heterocycle-rich molecular environment. Representative functionalizations of the enantioenriched pyridine N-oxides further document the utility of this approach. Demonstration of the asymmetric N-oxidation in two venerable drug-like scaffolds, Loratadine and Varenicline, show the likely generality of the method for highly variable and distinct chiral environments, while also revealing that the approach is applicable to both pyridines and 1,4-pyrazines.

Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof

Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts, pharmaceutical compositions containing them, and methods for the treatment of neurodegenerative disorders or neurotoxic injuries utilizing them, wherein the substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts have the formula: STR1 wherein: R1, R2, R3, R4, R5, R6, R7, X and p are as defined in the specification.