6852-58-0 Usage
Description
2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE is an organic compound that is derived from the in vitro metabolism of N-benzyl-tert-butylamine in male hamster hepatic microsomal preparations. It is a colorless to yellow liquid and has been studied in the context of frustrated Lewis pair (FLP)-catalyzed hydrogenation and deuteration, where it is suggested to proceed via autoinductive catalysis.
Uses
Used in Chemical Synthesis:
2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE is used as an intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical and chemical industries. Its unique structure allows for further functionalization and modification, making it a versatile building block for the development of new molecules with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE is used as a starting material for the development of new drugs. Its reactivity and structural properties make it a promising candidate for the design of novel therapeutic agents, particularly in the areas of central nervous system disorders, cardiovascular diseases, and oncology.
Used in Catalyst Development:
The study of frustrated Lewis pair (FLP)-catalyzed hydrogenation and deuteration of 2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE has implications for the development of new catalysts. Understanding the autoinductive catalysis mechanism can lead to the design of more efficient and selective catalysts for various chemical reactions, which can be applied across different industries, including petrochemicals, materials science, and environmental remediation.
Used in Analytical Chemistry:
As a colorless to yellow liquid with specific chemical properties, 2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE can be used as a reference compound or standard in analytical chemistry. It can be employed in the calibration of instruments, the development of new analytical methods, or the validation of existing techniques for the detection and quantification of similar compounds in complex samples.
Check Digit Verification of cas no
The CAS Registry Mumber 6852-58-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,5 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6852-58:
(6*6)+(5*8)+(4*5)+(3*2)+(2*5)+(1*8)=120
120 % 10 = 0
So 6852-58-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H15N/c1-11(2,3)12-9-10-7-5-4-6-8-10/h4-9H,1-3H3
6852-58-0Relevant articles and documents
Supramolecular Engineering of Discrete Pt(II)?Pt(II) Interactions for Visible-Light Photocatalysis
Li, Zijian,Han, Yifei,Gao, Zongchun,Wang, Feng
, p. 4676 - 4681 (2017)
Visible-light photosensitizers have emerged as a sustainable and environmentally friendly medium for organic transformation. Herein, we have developed a supramolecular strategy for manipulating visible-light photosensitization and photocatalytic efficienc
Expanding Coefficient: A Parameter to Assess the Stability of Induced-Fit Complexes
Talotta, Carmen,Concilio, Gerardo,De Rosa, Margherita,Soriente, Annunziata,Gaeta, Carmine,Rescifina, Antonio,Ballester, Pablo,Neri, Placido
supporting information, p. 1804 - 1808 (2021/03/08)
Here we propose a new parameter, the Expanding Coefficient (EC), that can be correlated with the thermodynamic stability of supramolecular complexes governed by weak secondary interactions and obeying the induced-fit model. The EC values show a good linear relationship with the log Kapp of the respective pseudorotaxane complexes investigated. According to Cram's Principle of Preorganization, the EC can be considered an approximate mechanical measure of the host's reorganization energy cost upon adopting the final bound geometry.
Transient imine as a directing group for the metal-free o-C-H borylation of benzaldehydes
Rej, Supriya,Chatani, Naoto
supporting information, p. 2920 - 2929 (2021/03/01)
Organoboron reagents are important synthetic intermediates and have wide applications in synthetic organic chemistry. The selective borylation strategies that are currently in use largely rely on the use of transition-metal catalysts. Hence, identifying much milder conditions for transition-metal-free borylation would be highly desirable. We herein present a unified strategy for the selective C-H borylation of electron-deficient benzaldehyde derivatives using a simple metal-free approach, utilizing an imine transient directing group. The strategy covers a wide spectrum of reactions and (i) even highly sterically hindered C-H bonds can be borylated smoothly, (ii) despite the presence of other potential directing groups, the reaction selectively occurs at the o-C-H bond of the benzaldehyde moiety, and (iii) natural products appended to benzaldehyde derivatives can also give the appropriate borylated products. Moreover, the efficacy of the protocol was confirmed by the fact that the reaction proceeds even in the presence of a series of external impurities.
