6851-51-0 Usage
Description
N-carbamoylputrescine is an organic compound that belongs to the class of chemicals known as polyamines, which are small compounds having more than two amine groups. It is an important intermediate in the production of polyamines in plants. This chemical is not naturally found in humans but is important in certain organisms and biological processes given its role in polyamine biosynthesis. It is produced from the reaction of putrescine and carbamoyl phosphate, catalyzed by the enzyme arginine decarboxylase, and is also involved in arginine and proline metabolism, behaving as both a substrate and product in its biochemical pathways. In terms of physical properties, it usually exists as a solid and its molecular weight is around 145.2 g/mol.
Uses
Used in Pharmaceutical Industry:
N-carbamoylputrescine is used as an intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its role in polyamine biosynthesis makes it a key component in the development of drugs targeting certain biological processes.
Used in Agricultural Industry:
N-carbamoylputrescine is used as a growth regulator in plants for [application reason]. Its involvement in the production of polyamines, which are essential for plant growth and development, makes it a valuable tool in enhancing crop yields and improving plant health.
Used in Biochemical Research:
N-carbamoylputrescine is used as a research compound in biochemical studies for [application reason]. Its involvement in various metabolic pathways and its role as a substrate and product in biochemical reactions make it an important molecule for understanding cellular processes and mechanisms.
Used in Chemical Synthesis:
N-carbamoylputrescine is used as a building block in the synthesis of complex organic compounds for [application reason]. Its unique structure and reactivity make it a valuable component in the creation of new molecules with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 6851-51-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,5 and 1 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6851-51:
(6*6)+(5*8)+(4*5)+(3*1)+(2*5)+(1*1)=110
110 % 10 = 0
So 6851-51-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H13N3O/c6-3-1-2-4-8-5(7)9/h1-4,6H2,(H3,7,8,9)
6851-51-0Relevant articles and documents
Characterization and inactivation of an agmatine deiminase from Helicobacter pylori
Jones, Justin E.,Causey, Corey P.,Lovelace, Leslie,Knuckley, Bryan,Flick, Heather,Lebioda, Lukasz,Thompson, Paul R.
, p. 62 - 73 (2010)
Helicobacter pylori encodes a potential virulence factor, agmatine deiminase (HpAgD), which catalyzes the conversion of agmatine to N-carbamoyl putrescine (NCP) and ammonia - agmatine is decarboxylated arginine. Agmatine is an endogenous human cell signaling molecule that triggers the innate immune response in humans. Unlike H. pylori, humans do not encode an AgD; it is hypothesized that inhibition of this enzyme would increase the levels of agmatine, and thereby enhance the innate immune response. Taken together, these facts suggest that HpAgD is a potential drug target. Herein we describe the optimized expression, isolation, and purification of HpAgD (10-30 mg/L media). The initial kinetic characterization of this enzyme has also been performed. Additionally, the crystal structure of wild-type HpAgD has been determined at 2.1 A resolution. This structure provides a molecular basis for the preferential deimination of agmatine, and identifies Asp198 as a key residue responsible for agmatine recognition, which has been confirmed experimentally. Information gathered from these studies led to the development and characterization of a novel class of haloacetamidine-based HpAgD inactivators. These compounds are the most potent AgD inhibitors ever described.
