683276-64-4

Basic information

• Product Name: R-2-METHYL GLYCIDYL P-NOSYLATE
• Synonyms: R-2-METHYL GLYCIDYL P-NOSYLATE;Benzenesulfonic acid, 4-nitro-, [(2R)-2-Methyloxiranyl]Methyl ester;(R)-(2-methyloxiran-2-yl)methyl 4-nitrobenzenesulfonate;(R)-2-methyl glycidyl para-nitro benzenesulfonate
• CAS NO: 683276-64-4
• Molecular Formula: C₁₀H₁₁NO₆S
• Molecular Weight: 273.264
• Mol File: 683276-64-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 429.9±20.0 °C(Predicted)
• Appearance: /
• Density: 1.452±0.06 g/cm3(Predicted)
• CAS DataBase Reference: R-2-METHYL GLYCIDYL P-NOSYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: R-2-METHYL GLYCIDYL P-NOSYLATE(683276-64-4)
• EPA Substance Registry System: R-2-METHYL GLYCIDYL P-NOSYLATE(683276-64-4)

Safety Data

• Hazardous Substances Data: 683276-64-4(Hazardous Substances Data)

Usage

Description

R-2-METHYL GLYCIDYL P-NOSYLATE is a chemical compound that serves as a reagent in organic synthesis, belonging to the class of glycidyl ethers. It is characterized by a 2-methyl glycidyl group and a p-nosylate group, which contribute to its reactivity and selectivity in specific chemical reactions. Known for its stability and compatibility with a wide range of organic solvents, R-2-METHYL GLYCIDYL P-NOSYLATE is a versatile tool in organic chemistry for the modification and manipulation of complex molecules, particularly for the protection of hydroxyl groups in organic molecules.

Uses

Used in Organic Synthesis:
R-2-METHYL GLYCIDYL P-NOSYLATE is used as a reagent for the protection of hydroxyl groups in organic molecules, facilitating the synthesis of complex organic compounds by preventing unwanted reactions at the hydroxyl sites.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, R-2-METHYL GLYCIDYL P-NOSYLATE is used as a protecting group agent for the synthesis of active pharmaceutical ingredients, ensuring the selective formation of desired compounds and improving the overall yield and purity of the final product.
Used in Chemical Research:
R-2-METHYL GLYCIDYL P-NOSYLATE is utilized in chemical research for the study of reaction mechanisms and the development of new synthetic methods, taking advantage of its reactivity and selectivity in specific chemical reactions.
Used in Material Science:
In material science, R-2-METHYL GLYCIDYL P-NOSYLATE is employed in the synthesis of novel materials with unique properties, such as polymers, coatings, and adhesives, by protecting hydroxyl groups during the formation of these materials.
Used in Analytical Chemistry:
R-2-METHYL GLYCIDYL P-NOSYLATE is used in analytical chemistry for the derivatization of compounds, enhancing their detection and analysis by chromatographic or spectroscopic techniques, particularly when dealing with polar or hydroxyl-containing molecules.

Upstream product

• 86884-90-4 (S)-2-methylglycidol 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 

Downstream Products

• 1083099-35-7 (R)-1-(4-((2-methyloxiran-2-yl)-methoxy)phenyl)-4-(4-(trifluoro-methoxy)phenoxy)piperidine 

Relevant articles and documents

Using an asymmetric flow reactor sharples

PROBLEM TO BE SOLVED: To provide a method for efficiently progressing a Sharpless asymmetric epoxidation even without adding molecular sieves. SOLUTION: The method for producing an optically active epoxyalcohol compound includes mixing an allyl alcohol compound, a titanium tetraalkoxide in a catalytic amount, an optically active tartaric acid ester in a catalytic amount, and an oxidizing agent, in a solvent by using a flow-type reactor (flow reactor). The oxidizing agent is preferably tert-butyl hydroperoxide or cumene hydroperoxide. COPYRIGHT: (C)2013,JPOandINPIT